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Claudin 2 (CLDN2) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855328

MBS855328 is an antibody targeting CLDN2. Also known as Claudin 2 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Claudin 2 (CLDN2), Antibody
Full Product Name
Claudin 2 Antibody
Product Gene Name
Product Synonym Names
CLD2; SP82
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Claudin 2 antibody detects endogenous levels of total Claudin 2 protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
24,549 Da
OMIM
300520
3D Structure
ModBase 3D Structure for P57739
Immunogen
The antiserum was produced against synthesized peptide derived from human Claudin 2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLDN2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CLDN2 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:5000

Immunohistochemistry (IHC) of anti-CLDN2 antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Claudin 2 antibody.
Anti-CLDN2 Antibody – Cat# MBS855328

Western Blot (WB) of anti-CLDN2 antibody

Western blot analysis of extracts from NIH/3T3 cells, using Claudin 2 antibody.
Anti-CLDN2 Antibody, Western Blot (WB) – Cat# MBS855328

Product References and Citations for anti-CLDN2 antibody

Michele A. Battle, PNAS, May 2006; 103: 8419-8424. Masahiko Itoh J. Cell Biol., Dec 1999; 147: 1351. Salah Amasheh, J. Cell Sci., Dec 2002; 115: 4969. Evemie Dubé, Biol Reprod, Apr 2007; 10.1095/biolreprod.106.059246.

Other Notes

Small volumes of anti-CLDN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
claudin-2
NCBI Official Synonym Full Names
claudin 2
NCBI Official Symbol
CLDN2
UniProt Protein Name
Claudin-2
UniProt Synonym Protein Names
SP82
Protein Family
UniProt Gene Name
CLDN2
NCBI Protein Information
claudin-2

NCBI Summary for CLDN2

This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
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UniProt Comments for CLDN2

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLDN2 antibody

 Reference Product  PubMed Publications
 TJP1 antibody  >46 publications with CLDN2 and TJP1
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