• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CLN5 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855466

MBS855466 is an antibody targeting CLN5. Also known as CLN5 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLN5, Antibody
Full Product Name
CLN5 Antibody
Product Gene Name
Product Synonym Names
Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CLN5 antibody detects endogenous levels of total CLN5 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
41,497 Da
OMIM
256731
3D Structure
ModBase 3D Structure for O75503
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CLN5.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLN5 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CLN5 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-CLN5 antibody

Western blot analysis of extracts from LOVO cells, using CLN5 antibody.
Anti-CLN5 Antibody – Cat# MBS855466

Product References and Citations for anti-CLN5 antibody

Savukoski M., Nat. Genet. 19:286-288(1998). Dunham A., Nature 428:522-528(2004).

Other Notes

Small volumes of anti-CLN5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLN5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ceroid-lipofuscinosis neuronal protein 5
NCBI Official Synonym Full Names
CLN5, intracellular trafficking protein
NCBI Official Symbol
CLN5
NCBI Official Synonym Symbols
NCL
UniProt Protein Name
Ceroid-lipofuscinosis neuronal protein 5
UniProt Gene Name
CLN5
UniProt Synonym Gene Names
Protein CLN5
NCBI Protein Information
ceroid-lipofuscinosis neuronal protein 5

NCBI Summary for CLN5

This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008]
Show more

UniProt Comments for CLN5

Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CLN5 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000