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GTF2IRD1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855493

MBS855493 is an antibody targeting GTF2IRD1. Also known as GTF2IRD1 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GTF2IRD1, Antibody
Full Product Name
GTF2IRD1 Antibody
Product Gene Name
Product Synonym Names
CREAM1; G2D1; GT2D1; GTF2I repeat domain containing protein 1; GTF2IRD1; GTF3; General transcription factor II-I repeat domain-containing protein 1; General transcription factor III; MUSTRD1; MusTRD1/BEN; Muscle TFII-I repeat domain-containing protein 1; RBAP2; Slow-muscle-fiber enhancer binding protein; USE B1 binding protein; WBSCR11; Williams-Beuren syndrome chromosome region 11 protein
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GTF2IRD1 antibody detects endogenous levels of total GTF2IRD1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
107,979 Da
OMIM
604318
3D Structure
ModBase 3D Structure for Q9UHL9
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human GTF2IRD1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GTF2IRD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GTF2IRD1 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-GTF2IRD1 antibody

Western blot analysis of extracts from 293 cells, using GTF2IRD1 antibody.
Anti-GTF2IRD1 Antibody – Cat# MBS855493

Product References and Citations for anti-GTF2IRD1 antibody

Yan X., Biochem. J. 345:749-757(2000). Hillier L.W., Nature 424:157-164(2003). Tussie-Luna M.I., Proc. Natl. Acad. Sci. U.S.A. 98:7789-7794(2001).

Other Notes

Small volumes of anti-GTF2IRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2IRD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
general transcription factor II-I repeat domain-containing protein 1 isoform 3
NCBI Official Synonym Full Names
GTF2I repeat domain containing 1
NCBI Official Symbol
GTF2IRD1
NCBI Official Synonym Symbols
BEN; WBS; GTF3; RBAP2; CREAM1; MUSTRD1; WBSCR11; WBSCR12; hMusTRD1alpha1
UniProt Protein Name
General transcription factor II-I repeat domain-containing protein 1
UniProt Synonym Protein Names
General transcription factor III; MusTRD1/BEN; Muscle TFII-I repeat domain-containing protein 1; Slow-muscle-fiber enhancer-binding protein; USE B1-binding protein; Williams-Beuren syndrome chromosomal region 11 protein; Williams-Beuren syndrome chromosomal region 12 protein
UniProt Gene Name
GTF2IRD1
UniProt Synonym Gene Names
CREAM1; GTF3; MUSTRD1; RBAP2; WBSCR11; WBSCR12; GTF2I repeat domain-containing protein 1
NCBI Protein Information
general transcription factor II-I repeat domain-containing protein 1

NCBI Summary for GTF2IRD1

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
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UniProt Comments for GTF2IRD1

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GTF2IRD1 antibody

 Reference Product  PubMed Publications
 SMAD3 antibody  >1 publications with GTF2IRD1 and SMAD3
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