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S6K-alpha2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855521

MBS855521 is an antibody targeting S6K-alpha2. Also known as S6K-alpha2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
S6K-alpha2, Antibody
Full Product Name
S6K-alpha2 Antibody
Product Gene Name
Product Synonym Names
90 kDa ribosomal protein S6 kinase 2; EC 2.7.11.1; KS6A2; RPS6KA2; RSK-3; Ribosomal S6 kinase 3; Ribosomal protein S6 kinase alpha 2; S6K-alpha 2; kinase RSK3; p90-RSK 2; pp90RSK3
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
S6K-alpha2 antibody detects endogenous levels of total S6K-alpha2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
84,014 Da
OMIM
601685
3D Structure
ModBase 3D Structure for Q15349
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human S6K-alpha2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-S6K-alpha2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-S6K-alpha2 antibody
IHC: 1:50-1:100
ELISA: 1:1000

Immunohistochemistry (IHC) of anti-S6K-alpha2 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using S6K-alpha2 antibody.
Anti-S6K-alpha2 Antibody – Cat# MBS855521

Product References and Citations for anti-S6K-alpha2 antibody

Zhao Y., Mol. Cell. Biol. 15:4353-4363(1995). Mungall A.J., Nature 425:805-811(2003). Denis N.J., Proteomics 7:868-874(2007).

Other Notes

Small volumes of anti-S6K-alpha2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for S6K-alpha2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ribosomal protein S6 kinase alpha-2 isoform b
NCBI Official Synonym Full Names
ribosomal protein S6 kinase A2
NCBI Official Symbol
RPS6KA2
NCBI Official Synonym Symbols
RSK; HU-2; RSK3; p90RSK2; p90-RSK3; pp90RSK3; MAPKAPK1C; S6K-alpha; S6K-alpha2
UniProt Protein Name
Ribosomal protein S6 kinase alpha-2
UniProt Synonym Protein Names
90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ribosomal S6 kinase 3; RSK-3; pp90RSK3
UniProt Gene Name
RPS6KA2
UniProt Synonym Gene Names
MAPKAPK1C; RSK3; S6K-alpha-2; p90-RSK 2; p90RSK2; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; RSK-3
NCBI Protein Information
ribosomal protein S6 kinase alpha-2

NCBI Summary for S6K-alpha2

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2016]
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UniProt Comments for S6K-alpha2

Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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