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SENP3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855585

MBS855585 is an antibody targeting SENP3. Also known as SENP3 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SENP3, Antibody
Full Product Name
SENP3 Antibody
Product Gene Name
Product Synonym Names
Sentrin-specific protease 3; EC=3.4.22.-; Sentrin/SUMO-specific protease SENP3; SUMO-1-specific protease 3; SSP3; SUSP3
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
SENP3 antibody detects endogenous levels of total SENP3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
65,010 Da
OMIM
612844
3D Structure
ModBase 3D Structure for Q9H4L4
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human SENP3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SENP3 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-SENP3 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Testing Data of anti-SENP3 antibody

Peptide-+
Anti-SENP3 Antibody – Cat# MBS855585

Immunohistochemistry (IHC) of anti-SENP3 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP3 antibody. Western blot analysis of extracts from Jurkat cells, using SENP3 antibody.
Anti-SENP3 Antibody, Immunohistochemistry (IHC) – Cat# MBS855585

Product References and Citations for anti-SENP3 antibody

Yeh E.T.H., Gene 248:1-14(2000). Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases. Wiemann S., Genome Res. 11:422-435(2001).

Other Notes

Small volumes of anti-SENP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SENP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sentrin-specific protease 3
NCBI Official Synonym Full Names
SUMO specific peptidase 3
NCBI Official Symbol
SENP3
NCBI Official Synonym Symbols
SSP3; Ulp1; SMT3IP1
UniProt Protein Name
Sentrin-specific protease 3
UniProt Synonym Protein Names
SUMO-1-specific protease 3; Sentrin/SUMO-specific protease SENP3
UniProt Gene Name
SENP3
UniProt Synonym Gene Names
SSP3; SUSP3
NCBI Protein Information
sentrin-specific protease 3

NCBI Summary for SENP3

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
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UniProt Comments for SENP3

Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SENP3 antibody

Organs/Tissues associated with anti-SENP3 antibody

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