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TF2A1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855657

MBS855657 is an antibody targeting TF2A1. Also known as TF2A1 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TF2A1, Antibody
Full Product Name
TF2A1 Antibody
Product Gene Name
anti-TF2A1 antibody
Product Synonym Names
Transcription initiation factor IIA subunit 1; General transcription factor IIA subunit 1; TFIIA-42; TFIIAL; Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit); GTF2A1; TF2A1
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TF2A1 antibody detects endogenous levels of total TF2A1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
37,152 Da
OMIM
600520
3D Structure
ModBase 3D Structure for P52655
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human TF2A1.

Product Categories/Family for anti-TF2A1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TF2A1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TF2A1 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-TF2A1 antibody

Western blot analysis of extracts from RAW264.7 cells, using TF2A1 antibody.
Anti-TF2A1 Antibody – Cat# MBS855657

Product References and Citations for anti-TF2A1 antibody

Ma D., Genes Dev. 7:2246-2257(1993). Dejong J., Genes Dev. 7:2220-2234(1993). Heilig R., Nature 421:601-607(2003).

Other Notes

Small volumes of anti-TF2A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TF2A1. It may not necessarily be applicable to this product.

NCBI GI #
525313614
NCBI GeneID
2957
NCBI Accession #
NP_001265869.1
UniProt Primary Accession #
P52655
UniProt Secondary Accession #
Q3KNQ9
UniProt Related Accession #
P52655
GenBank Nucleotide #
NM_001278940.1
NCBI Official Full Name
transcription initiation factor IIA subunit 1 isoform 3
NCBI Official Synonym Full Names
general transcription factor IIA subunit 1
NCBI Official Symbol
GTF2A1
NCBI Official Synonym Symbols
TF2A1; TFIIA; TFIIAL; TFIIA-42
UniProt Protein Name
Transcription initiation factor IIA subunit 1
UniProt Synonym Protein Names
General transcription factor IIA subunit 1; TFIIAL; Transcription initiation factor TFIIA 42 kDa subunit; TFIIA-42
UniProt Gene Name
GTF2A1
UniProt Synonym Gene Names
TF2A1; TFIIA-42
NCBI Protein Information
transcription initiation factor IIA subunit 1

NCBI Summary for TF2A1

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]
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UniProt Comments for TF2A1

TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

Research Articles on TF2A1

1. In a cohort of youth at risk for bipolar disorder, pathway analysis showed an enrichment of the glucocorticoid receptor (GR) pathway with the genes MED1, HSPA1L, GTF2A1 and TAF15, which might underlie the previously reported role of stress response in the risk for bipolar disorder in vulnerable populations.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TF2A1 antibody

 Reference Product  PubMed Publications
 GTF2A2 antibody  >1 publications with TF2A1 and GTF2A2
 TBP antibody  >1 publications with TF2A1 and TBP

Pathways associated with anti-TF2A1 antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 HIV Transcription Initiation Pathway antibodies  HIV Transcription Initiation Pathway Diagram
 Late Phase Of HIV Life Cycle Pathway antibodies  Late Phase Of HIV Life Cycle Pathway Diagram
 RNA Polymerase II HIV Promoter Escape Pathway antibodies  RNA Polymerase II HIV Promoter Escape Pathway Diagram
 RNA Polymerase II Pre-transcription Events Pathway antibodies  RNA Polymerase II Pre-transcription Events Pathway Diagram

Diseases associated with anti-TF2A1 antibody

 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >1 publications with TF2A1 and Ovarian Neoplasms

Organs/Tissues associated with anti-TF2A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >1 publications with TF2A1 and Stomach
 Testis Antibodies  >1 publications with TF2A1 and Testis
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