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CMKLR1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855662

MBS855662 is an antibody targeting CMKLR1. Also known as CMKLR1 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CMKLR1, Antibody
Full Product Name
CMKLR1 Antibody
Product Gene Name
Product Synonym Names
Chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled receptor ChemR23; CHEMR23; DEZ; CML1
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CMKLR1 antibody detects endogenous levels of total CMKLR1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
42,035 Da
OMIM
602351
3D Structure
ModBase 3D Structure for Q99788
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CMKLR1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CMKLR1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CMKLR1 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-CMKLR1 antibody

Western blot analysis of extracts from HepG2 cells, HeLa cells and 293 cells, using CMKLR1 antibody.
Anti-CMKLR1 Antibody – Cat# MBS855662

Product References and Citations for anti-CMKLR1 antibody

Methner A., Biochem. Biophys. Res. Commun. 233:336-342(1997). Samson M., Eur. J. Immunol. 28:1689-1700(1998). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004).

Other Notes

Small volumes of anti-CMKLR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CMKLR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chemokine-like receptor 1 isoform a
NCBI Official Synonym Full Names
chemerin chemokine-like receptor 1
NCBI Official Symbol
CMKLR1
NCBI Official Synonym Symbols
DEZ; RVER1; ChemR23; CHEMERINR
UniProt Protein Name
Chemokine-like receptor 1
UniProt Synonym Protein Names
G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ
UniProt Gene Name
CMKLR1
UniProt Synonym Gene Names
CHEMR23; DEZ
NCBI Protein Information
chemokine-like receptor 1

UniProt Comments for CMKLR1

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CMKLR1 antibody

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