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NCR3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855719

MBS855719 is an antibody targeting NCR3. Also known as NCR3 Antibody. Reactive in Human, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NCR3, Antibody
Full Product Name
NCR3 Antibody
Product Gene Name
Product Synonym Names
Natural cytotoxicity triggering receptor 3; Natural killer cell p30-related protein; NKp30; NK-p30; Activating natural killer receptor p30; CD337 antigen
Species Reactivity
Human, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
NCR3 antibody detects endogenous levels of total NCR3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
16,393 Da
OMIM
609148
3D Structure
ModBase 3D Structure for O14931
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human NCR3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NCR3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-NCR3 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-NCR3 antibody

Western blot analysis of extracts from A549 cells, using NCR3 antibody. For Research Use Only
Anti-NCR3 Antibody – Cat# MBS855719

Product References and Citations for anti-NCR3 antibody

Pende D., J. Exp. Med. 190:1505-1516(1999). Sato M., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. Neville M.J., J. Immunol. 162:4745-4754(1999).

Other Notes

Small volumes of anti-NCR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NCR3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
natural cytotoxicity triggering receptor 3 isoform b
NCBI Official Synonym Full Names
natural cytotoxicity triggering receptor 3
NCBI Official Symbol
NCR3
NCBI Official Synonym Symbols
1C7; MALS; CD337; LY117; NKp30
UniProt Protein Name
Natural cytotoxicity triggering receptor 3
UniProt Synonym Protein Names
Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NKp30; CD_antigen: CD337
UniProt Gene Name
NCR3
UniProt Synonym Gene Names
1C7; LY117; NK-p30; NKp30
NCBI Protein Information
natural cytotoxicity triggering receptor 3

NCBI Summary for NCR3

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
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UniProt Comments for NCR3

Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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