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CD32 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855849

MBS855849 is an antibody targeting CD32. Also known as CD32 (Phospho-Tyr292) Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD32, Antibody
Full Product Name
CD32 (Phospho-Tyr292) Antibody
Product Gene Name
Product Synonym Names
CD32; CDW32; FC gamma receptor IIB; FC-gamma RII; FC-gamma RII-B; FC-gamma-RIIB; FCG2; FCG2B; FCGR2; FCGR2B; FCRII; FCgammaRIIB; IGFR2; IGG FC receptor II beta; IGG FC receptor II-B; LY-17; Low affinity immunoglobulin gamma FC region receptor II precursor; Low affinity immunoglobulin gamma FC region receptor II-B precursor
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
CD32 (Phospho-Tyr292) antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
31,873 Da
OMIM
152700
3D Structure
ModBase 3D Structure for P31994
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human CD32around the phosphorylation site of tyrosine 292 (I-T-YP-S-L).
All Sites
Human: Tyr292
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD32 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CD32 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-CD32 antibody

Western blot analysis of extracts from K562 cells, treated with PMA (125ng/ml, 30mins), using CD32 (Phospho-Tyr292) antibody.
Anti-CD32 Antibody – Cat# MBS855849

Product References and Citations for anti-CD32 antibody

Stuart S.G., EMBO J. 8:3657-3666(1989). Brooks D.G., J. Exp. Med. 170:1369-1385(1989). Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990).

Other Notes

Small volumes of anti-CD32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD32. It may not necessarily be applicable to this product.

UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-b
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD_antigen: CD32
Protein Family
UniProt Gene Name
FCGR2B
UniProt Synonym Gene Names
CD32; FCG2; IGFR2; IgG Fc receptor II-b; Fc-gamma-RIIb; FcRII-b

UniProt Comments for CD32

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.CautionHas sometimes been attributed to correspond to FcR-IIC.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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