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KLF Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855850

MBS855850 is an antibody targeting KLF. Also known as KLF Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLF, Antibody
Full Product Name
KLF Antibody
Product Gene Name
Product Synonym Names
Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF; Erythroid transcription factor; EKLF
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
KLF antibody detects endogenous levels of total KLF protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
38,221 Da
OMIM
111150
3D Structure
ModBase 3D Structure for Q13351
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KLF.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KLF antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-KLF antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-KLF antibody

Western blot analysis of extracts from Jurkat cells, treated with serum (20%, 15mins), using KLF antibody.
Anti-KLF Antibody – Cat# MBS855850

Product References and Citations for anti-KLF antibody

Bieker J.J., DNA Cell Biol. 15:347-352(1996). van Ree J.H., Genomics 39:393-395(1997). Grimwood J., Nature 428:529-535(2004).

Other Notes

Small volumes of anti-KLF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KLF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Krueppel-like factor 1
NCBI Official Synonym Full Names
Kruppel like factor 1
NCBI Official Symbol
KLF1
NCBI Official Synonym Symbols
EKLF
UniProt Protein Name
Krueppel-like factor 1
UniProt Synonym Protein Names
Erythroid krueppel-like transcription factor; EKLF
UniProt Gene Name
KLF1
UniProt Synonym Gene Names
EKLF; EKLF
NCBI Protein Information
Krueppel-like factor 1

NCBI Summary for KLF

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]
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UniProt Comments for KLF

Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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