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DNA Polymerase Zeta (REV3L) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855908

MBS855908 is an antibody targeting REV3L. Also known as DNA Polymerase zeta Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA Polymerase zeta (REV3L), Antibody
Full Product Name
DNA Polymerase zeta Antibody
Product Gene Name
Product Synonym Names
DNA polymerase zeta catalytic subunit; DPOLZ; DPOZ; EC 2.7.7.7; POLZ; REV3L; SEZ4; Seizure-related protein 4; hREV3
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
DNA Polymerase zeta antibody detects endogenous levels of total DNA Polymerase zeta protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
344,154 Da
OMIM
602776
3D Structure
ModBase 3D Structure for O60673
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DNA Polymerase zeta.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-REV3L antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-REV3L antibody
IHC: 1:50-1:100
ELISA: 1:40000

Immunohistochemistry (IHC) of anti-REV3L antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DNA Polymerase zeta antibody.
Anti-REV3L Antibody – Cat# MBS855908

Product References and Citations for anti-REV3L antibody

Gibbs P.E.M., Proc. Natl. Acad. Sci. U.S.A. 95:6876-6880(1998). Lin W., Mutat. Res. 433:89-98(1999). Morelli C., Cytogenet. Cell Genet. 83:18-20(1998).

Other Notes

Small volumes of anti-REV3L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for REV3L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA polymerase zeta catalytic subunit isoform b
NCBI Official Synonym Full Names
REV3 like, DNA directed polymerase zeta catalytic subunit
NCBI Official Symbol
REV3L
NCBI Official Synonym Symbols
POLZ; REV3
UniProt Protein Name
DNA polymerase zeta catalytic subunit
UniProt Synonym Protein Names
Protein reversionless 3-like; REV3-like; hREV3
Protein Family
UniProt Gene Name
REV3L
UniProt Synonym Gene Names
POLZ; REV3; REV3-like; hREV3
NCBI Protein Information
DNA polymerase zeta catalytic subunit

NCBI Summary for REV3L

The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]
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UniProt Comments for REV3L

Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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