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SENP2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856021

MBS856021 is an antibody targeting SENP2. Also known as SENP2 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SENP2, Antibody
Full Product Name
SENP2 Antibody
Product Gene Name
Product Synonym Names
Axam2; EC 3.4.22.-; SMT3-specific isopeptidase 2; SUMO1/sentrin/SMT3 specific peptidase 2; Smt3ip2; sentrin-specific protease
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
SENP2 antibody detects endogenous levels of total SENP2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
66,358 Da
OMIM
608261
3D Structure
ModBase 3D Structure for Q9HC62
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human SENP2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SENP2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SENP2 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-SENP2 antibody

Western blot analysis of extracts from MDA-MB-435cells, using SENP2 antibody.
Anti-SENP2 Antibody – Cat# MBS856021

Product References and Citations for anti-SENP2 antibody

Yoko Itahana, Mol. Cell. Biol., Jun 2006; 26: 4675-4689. Jinke Cheng, J. Biol. Chem., Apr 2005; 280: 14492-14498. Mark D. Benson, PNAS, Feb 2007; 104: 1805-1810.

Other Notes

Small volumes of anti-SENP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SENP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sentrin-specific protease 2
NCBI Official Synonym Full Names
SUMO specific peptidase 2
NCBI Official Symbol
SENP2
NCBI Official Synonym Symbols
AXAM2; SMT3IP2
UniProt Protein Name
Sentrin-specific protease 2
UniProt Synonym Protein Names
Axam2; SMT3-specific isopeptidase 2; Smt3ip2; Sentrin/SUMO-specific protease SENP2
UniProt Gene Name
SENP2
UniProt Synonym Gene Names
KIAA1331; Smt3ip2
NCBI Protein Information
sentrin-specific protease 2

NCBI Summary for SENP2

SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]

UniProt Comments for SENP2

Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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