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CKI-epsilon Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856410

MBS856410 is an antibody targeting CKI-epsilon. Also known as CKI-epsilon Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CKI-epsilon, Antibody
Full Product Name
CKI-epsilon Antibody
Product Gene Name
anti-CKI-epsilon antibody
Product Synonym Names
CK1-epsilon; CKI-epsilon; CKIe; CSNK1E; Casein kinase I; epsilon isoform; EC 2.7.11.1; KC1E; kinase CK1-epsilon
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CKI-epsilon antibody detects endogenous levels of total CKI-epsilon protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
47,315 Da
OMIM
600863
3D Structure
ModBase 3D Structure for P49674
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CKI-epsilon.

Product Categories/Family for anti-CKI-epsilon antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CKI-epsilon antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CKI-epsilon antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:20000

Testing Data of anti-CKI-epsilon antibody

Peptide-+
Anti-CKI-epsilon Antibody – Cat# MBS856410

Immunohistochemistry (IHC) of anti-CKI-epsilon antibody

Immunohistochemistry analysis of paraffin-embedded human placenta tissue using CKI-epsilon antibody. Western blot analysis of extracts from LOVO cells, using CKI-epsilon antibody.
Anti-CKI-epsilon Antibody, Immunohistochemistry (IHC) – Cat# MBS856410

Immunofluorescence (IF) of anti-CKI-epsilon antibody

Peptide-+ Immunofluorescence analysis of HeLa cells, using CKI-epsilon antibody.
Anti-CKI-epsilon Antibody, Immunofluorescence (IF) – Cat# MBS856410

Product References and Citations for anti-CKI-epsilon antibody

Fish K.J., J. Biol. Chem. 270:14875-14883(1995). Okamura A., Blood 103:2997-3004(2004). Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Other Notes

Small volumes of anti-CKI-epsilon antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CKI-epsilon. It may not necessarily be applicable to this product.

NCBI GI #
583966087
NCBI GeneID
102800317
NCBI Accession #
NP_001276841.1
UniProt Primary Accession #
P49674
GenBank Nucleotide #
NM_001289912.1
NCBI Official Full Name
casein kinase I isoform epsilon
NCBI Official Synonym Full Names
TPTEP2-CSNK1E readthrough
NCBI Official Symbol
TPTEP2-CSNK1E
NCBI Official Synonym Symbols
LOC400927-CSNK1E
UniProt Protein Name
Casein kinase I isoform epsilon
Protein Family
Casein kinase
UniProt Gene Name
CSNK1E
UniProt Synonym Gene Names
CKI-epsilon; CKIe
NCBI Protein Information
casein kinase I isoform epsilon

NCBI Summary for CKI-epsilon

This locus represents naturally occurring readthrough transcription between the neighboring LOC400927 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene) and CSNK1E (casein kinase I isoform epsilon) genes on chromosome 22. The readthrough transcript encodes the same protein as the downstream gene product (casein kinase I isoform epsilon). [provided by RefSeq, Feb 2014]
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UniProt Comments for CKI-epsilon

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
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Research Articles on CKI-epsilon

1. CKI-epsilon is a potent TDP-43 kinase in vivo and in vitro.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CKI-epsilon antibody

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 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
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