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CDKAP1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856598

MBS856598 is an antibody targeting CDKAP1. Also known as CDKAP1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDKAP1, Antibody
Full Product Name
CDKAP1 Antibody
Product Gene Name
Product Synonym Names
Cyclin-dependent kinase 2-associated protein 1; CDK2-associated protein 1; Putative oral cancer suppressor; Deleted in oral cancer 1; DOC-1; CDK2AP1; CDKAP1; DOC1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CDKA1antibody detects endogenous levels of total CDKA1protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
9,601 Da
OMIM
602198
3D Structure
ModBase 3D Structure for O14519
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CDKA1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CDKAP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CDKAP1 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-CDKAP1 antibody

Western blot analysis of extracts from HeLa cells, using CDKA1antibody.
Anti-CDKAP1 Antibody – Cat# MBS856598

Product References and Citations for anti-CDKAP1 antibody

Daigo Y., Genes Chromosomes Cancer 20:204-207(1997). Tsuji T., J. Biol. Chem. 273:6704-6709(1998). The MGC Project Team, Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-CDKAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDKAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase 2-associated protein 1 isoform 2
NCBI Official Synonym Full Names
cyclin dependent kinase 2 associated protein 1
NCBI Official Symbol
CDK2AP1
NCBI Official Synonym Symbols
DOC1; ST19; DORC1; doc-1; p12DOC-1
UniProt Protein Name
Cyclin-dependent kinase 2-associated protein 1
UniProt Synonym Protein Names
Deleted in oral cancer 1; DOC-1; Putative oral cancer suppressor
UniProt Gene Name
CDK2AP1
UniProt Synonym Gene Names
CDKAP1; DOC1; CDK2-associated protein 1; DOC-1
NCBI Protein Information
cyclin-dependent kinase 2-associated protein 1

NCBI Summary for CDKAP1

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
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UniProt Comments for CDKAP1

specific inhibitor of the cell-cycle kinase CDK2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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