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CPI17alpha Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857460

MBS857460 is an antibody targeting CPI17alpha. Also known as CPI17alpha (Ab-38) Antibody. Reactive in Human, Mouse, Rat. More details

$235 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CPI17alpha, Antibody
Full Product Name
CPI17alpha (Ab-38) Antibody
Product Gene Name
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CPI17alpha (Ab-38) antibody detects endogenous levels of total CPI17alpha protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
13,480 Da
OMIM
608153
3D Structure
ModBase 3D Structure for Q96A00
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human CPI17alpha around the phosphorylation site of threonine 38 (R-V-TP-V-K).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CPI17alpha antibody
Immunofluorescence (IF)
Application Notes for anti-CPI17alpha antibody
IF: 1:100-1:200

Testing Data of anti-CPI17alpha antibody

Immunofluorescence staining of methanol-fixed HeLa cells using CPI17alpha (Ab-38) antibody (E021281, Red).
Anti-CPI17alpha Antibody – Cat# MBS857460

Product References and Citations for anti-CPI17alpha antibody

Hagerty L, et al. (2007) J Biol Chem. 2007; 282(7):4884-93 Seok YM, et al. (2008) J Pharmacol Exp Ther. Niiro N et al. (2003) Biochem J. 2003; 369(Pt 1):117-28.

Other Notes

Small volumes of anti-CPI17alpha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CPI17alpha. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 14A isoform 2
NCBI Official Synonym Full Names
protein phosphatase 1 regulatory inhibitor subunit 14A
NCBI Official Symbol
PPP1R14A
NCBI Official Synonym Symbols
CPI17; CPI-17; PPP1INL
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 14A
UniProt Synonym Protein Names
17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17
UniProt Gene Name
PPP1R14A
UniProt Synonym Gene Names
CPI17; PPP1INL; CPI-17
NCBI Protein Information
protein phosphatase 1 regulatory subunit 14A

NCBI Summary for CPI17alpha

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]
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UniProt Comments for CPI17alpha

Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CPI17alpha antibody

 Reference Product  PubMed Publications
 PRKCA antibody  >2 publications with CPI17alpha and PRKCA
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