• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

p73 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857491

MBS857491 is an antibody targeting p73. Also known as p73 (Phospho-Tyr99) Antibody. Reactive in Human, Mouse, Rat. More details

$295 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
p73, Antibody
Full Product Name
p73 (Phospho-Tyr99) Antibody
Product Gene Name
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
p73 (phospho-Tyr99) antibody detects endogenous levels of p73 only when phosphorylated at tyrosine 99.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
61,694 Da
OMIM
601990
3D Structure
ModBase 3D Structure for O15350
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human p73 around the phosphorylation site of tyrosine 99 (S-P-YP-A-Q).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-p73 antibody
Western Blot (WB)
Application Notes for anti-p73 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-p73 antibody

Western blot analysis of extracts from K562 cells using p73 (Ab-99) antibody and p73 (phospho-Tyr99) antibody.
Anti-p73 Antibody – Cat# MBS857491

Product References and Citations for anti-p73 antibody

Yuan ZM, et al.(1999) Nature.399(6738): 814-817.

Other Notes

Small volumes of anti-p73 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for p73. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor protein p73 isoform b
NCBI Official Synonym Full Names
tumor protein p73
NCBI Official Symbol
TP73
NCBI Official Synonym Symbols
P73
UniProt Protein Name
Tumor protein p73
UniProt Synonym Protein Names
p53-like transcription factor; p53-related protein
Protein Family
UniProt Gene Name
TP73
UniProt Synonym Gene Names
P73
NCBI Protein Information
tumor protein p73

NCBI Summary for p73

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]
Show more

UniProt Comments for p73

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000