PGC Antibody

Name: PGC Antibody; MyBioSource
Brand: MyBioSource
SKU: MBS857560
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857560

MBS857560 is an antibody targeting PGC. Also known as PGC (pepsinogen-II, PG-II) Antibody. More details

$380 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PGC (pepsinogen-II, PG-II), Antibody

Full Product Name

PGC (pepsinogen-II, PG-II) Antibody

Product Gene Name

anti-PGC antibody

Isotype

IgG

Form/Format

In PBS, pH 7.4 + 0.2

Purity/Purification

>95% pure (SDS-PAGE).
Protein G chromatography. Product is 0.2um filtered.

Specificity

Recognizes an epitope on the PGC (pepsinogen-II, PG-II).

Preparation and Storage

Short-term store at 2-8 degree C. Long term store at-20 degree C. Avoid multiple freeze/thaw cycles

Molecular Weight

34,208 Da

OMIM

169740

Immunogen

PGC antigen

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PGC antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-PGC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PGC. It may not necessarily be applicable to this product.

NCBI GI #

27503535

NCBI GeneID

5225

NCBI Accession #

AAH42578.1

UniProt Secondary Accession #

Q5T3D7; Q5T3D8; B4DVZ3

UniProt Related Accession #

P20142

NCBI Official Full Name

PGC protein

NCBI Official Synonym Full Names

progastricsin

NCBI Official Symbol

PGC

NCBI Official Synonym Symbols

PEPC; PGII

UniProt Protein Name

Gastricsin

UniProt Synonym Protein Names

Pepsinogen C

Protein Family

Gastricsin

UniProt Gene Name

PGC

NCBI Protein Information

gastricsin

NCBI Summary for PGC

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]

UniProt Comments for PGC

Hydrolyzes a variety of proteins.

Research Articles on PGC

1. serum levels correlated with age, sex and the level of Helicobacter pylori infection

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PGC antibody

Reference Product	PubMed Publications
PGD antibody	>9 publications with PGC and PGD
PCK1 antibody	>8 publications with PGC and PCK1
ESR1 antibody	>1 publications with PGC and ESR1
PCK2 antibody	>1 publications with PGC and PCK2

Diseases associated with anti-PGC antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>260 publications with PGC and Nervous System Diseases
Cardiovascular Diseases Antibodies	>242 publications with PGC and Cardiovascular Diseases
Disease Models, Animal Antibodies	>232 publications with PGC and Disease Models, Animal
Inflammation Antibodies	>191 publications with PGC and Inflammation
Fatty Liver Antibodies	>184 publications with PGC and Fatty Liver
Liver Diseases Antibodies	>144 publications with PGC and Liver Diseases
Heart Diseases Antibodies	>139 publications with PGC and Heart Diseases
Hypertrophy Antibodies	>106 publications with PGC and Hypertrophy
Necrosis Antibodies	>104 publications with PGC and Necrosis
Atrophy Antibodies	>103 publications with PGC and Atrophy

Organs/Tissues associated with anti-PGC antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>513 publications with PGC and Liver
Heart Antibodies	>339 publications with PGC and Heart
Brain Antibodies	>280 publications with PGC and Brain
Connective Tissue Antibodies	>218 publications with PGC and Connective Tissue
Stomach Antibodies	>82 publications with PGC and Stomach
Pancreas Antibodies	>54 publications with PGC and Pancreas
Lung Antibodies	>43 publications with PGC and Lung
Prostate Antibodies	>15 publications with PGC and Prostate
Esophagus Antibodies	>4 publications with PGC and Esophagus
Uncharacterized Tissue Antibodies	>1 publications with PGC and Uncharacterized Tissue