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SMAD5 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857801

SMAD5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. It is a receptor-regulated SMAD (R-SMAD), and acts as an intracellular signal transducer for the transforming growth factor beta superfamily. SMAD5 is activated through serine… More details

$295 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMAD5, Antibody
Full Product Name
SMAD5 Antibody
Product Gene Name
Product Synonym Names
Mouse monoclonal IgG to SMAD5
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Protein G-Sepharose affinity purified.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
52,258 Da
OMIM
603110
3D Structure
ModBase 3D Structure for Q99717
Immunogen
Recombinant fragment of human SMAD5 (C-terminus).
Preservative
0.02% Sodium Azide and 50% glycerol. 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SMAD5 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-SMAD5 antibody
ELISA: 1:5000-1:20000
WB: 1:100-1:2000

Testing Data of anti-SMAD5 antibody

SMAD5 (C-terminus) antibody at 1/2000 dilution interacts with recombinant SMAD5 protein with a DsbA tag. Predicted band size: 40KDa. Observed band size: 40KDa.
Anti-SMAD5 Antibody – Cat# MBS857801

Other Notes

Small volumes of anti-SMAD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMAD5 purchase

MBS857801 is an antibody targeting SMAD5. Also known as SMAD5 Antibody. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for SMAD5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mothers against decapentaplegic homolog 5
NCBI Official Synonym Full Names
SMAD family member 5
NCBI Official Symbol
SMAD5
NCBI Official Synonym Symbols
DWFC; JV5-1; MADH5
UniProt Protein Name
Mothers against decapentaplegic homolog 5
UniProt Synonym Protein Names
JV5-1; SMAD family member 5; SMAD 5; Smad5; hSmad5
UniProt Gene Name
SMAD5
UniProt Synonym Gene Names
MADH5; MAD homolog 5; Mothers against DPP homolog 5; SMAD 5; Smad5; hSmad5
NCBI Protein Information
mothers against decapentaplegic homolog 5

NCBI Summary for SMAD5

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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UniProt Comments for SMAD5

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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