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HK1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857948

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been… More details

$400 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HK1, Monoclonal Antibody
Full Product Name
HK1 (Hexokinase-1) Antibody
Product Gene Name
Product Synonym Gene Name
HKI; HXK1; HK1-ta; HK1-tb; HK1-tc
Product Synonym Names
HK I; glycolytic enzyme; hexokinase type I brain form hexokinase
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Form/Format
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Purity/Purification
Affinity purified
Specificity
This antibody detects endogenous levels of HK1 and does not cross-react with related proteins.
Molecular Weight
102kDa
OMIM
142600
3D Structure
ModBase 3D Structure for P19367
Immunogen
Purified recombinant human HK1 protein fragments expressed in E Coli.
Cellular Localization
Mitochondrion outer membrane
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HK1 antibody
Western Blot (WB), Immunocytochemistry (ICC)

Testing Data of anti-HK1 antibody

Immunocytochemistry stain of Hela using HK1 antibody (1:300).
Mouse Anti-HK1 Monoclonal Antibody – Cat# MBS857948

Testing Data #2 of anti-HK1 antibody

Western blot detection of HK1 in Hela&Jurkat cell lysates using HK1 antibody (1:10000 diluted). Predicted band size: 102kDa Observed band size: 102kDa
Mouse Anti-HK1 Monoclonal Antibody, Testing Data #2 – Cat# MBS857948

Other Notes

Small volumes of anti-HK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HK1 purchase

MBS857948 is an antibody targeting HK1. Also known as HK1 (Hexokinase-1) Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hexokinase-1 isoform HKI
NCBI Official Synonym Full Names
hexokinase 1
NCBI Official Symbol
HK1
NCBI Official Synonym Symbols
HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase
UniProt Protein Name
Hexokinase-1
UniProt Synonym Protein Names
Brain form hexokinase; Hexokinase type I; HK I
UniProt Gene Name
HK1
UniProt Synonym Gene Names
HK I
NCBI Protein Information
hexokinase-1

NCBI Summary for HK1

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016]
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UniProt Comments for HK1

MiscellaneousIn vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HK1 antibody

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