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GALR1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS858010

MBS858010 is an antibody targeting GALR1. Also known as GALR1 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GALR1, Antibody
Full Product Name
GALR1 Antibody
Product Gene Name
anti-GALR1 antibody
Product Synonym Names
Galanin receptor type 1; GAL1-R; GALR1; GALR1; GALNR; GALNR1
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GALR1 antibody detects endogenous levels of total GALR1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
38,953 Da
OMIM
600377
3D Structure
ModBase 3D Structure for P47211
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GALR1.

Product Categories/Family for anti-GALR1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GALR1 antibody
Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GALR1 antibody
IF: 1:100-1:500
ELISA: 1:5000

Immunofluorescence (IF) of anti-GALR1 antibody

Peptide-+ Immunofluorescence analysis of LOVO cells, using GALR1 antibody.
Anti-GALR1 Antibody – Cat# MBS858010

Product References and Citations for anti-GALR1 antibody

Habert-Ortoli E., Proc. Natl. Acad. Sci. U.S.A. 91:9780-9783(1994). Lorimer D.D., Biochem. Biophys. Res. Commun. 241:558-564(1997). Jacoby A.S., Genomics 45:496-508(1997).

Other Notes

Small volumes of anti-GALR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GALR1. It may not necessarily be applicable to this product.

NCBI GI #
167000885
NCBI GeneID
2587
NCBI Accession #
NP_001471.2
UniProt Primary Accession #
P47211
UniProt Secondary Accession #
Q4VBL7
UniProt Related Accession #
P47211
GenBank Nucleotide #
NM_001480.3
NCBI Official Full Name
galanin receptor type 1
NCBI Official Synonym Full Names
galanin receptor 1
NCBI Official Symbol
GALR1
NCBI Official Synonym Symbols
GALNR; GALNR1
UniProt Protein Name
Galanin receptor type 1
Protein Family
Galanin receptor
UniProt Gene Name
GALR1
UniProt Synonym Gene Names
GALNR; GALNR1; GAL1-R; GALR-1
NCBI Protein Information
galanin receptor type 1

NCBI Summary for GALR1

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]
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UniProt Comments for GALR1

Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

Research Articles on GALR1

1. High methylation of GALR1 is associated with head and neck cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GALR1 antibody

 Reference Product  PubMed Publications
 GAL antibody  >49 publications with GALR1 and GAL

Pathways associated with anti-GALR1 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-GALR1 antibody

 Disease Name  Pubmed Publications
 Seizures Antibodies  >19 publications with GALR1 and Seizures
 Inflammation Antibodies  >8 publications with GALR1 and Inflammation
 Disease Models, Animal Antibodies  >7 publications with GALR1 and Disease Models, Animal
 Necrosis Antibodies  >4 publications with GALR1 and Necrosis
 Learning Disorders Antibodies  >3 publications with GALR1 and Learning Disorders
 Drug Toxicity Antibodies  >3 publications with GALR1 and Drug Toxicity
 Memory Disorders Antibodies  >2 publications with GALR1 and Memory Disorders
 Body Weight Changes Antibodies  >2 publications with GALR1 and Body Weight Changes
 Weight Loss Antibodies  >2 publications with GALR1 and Weight Loss
 Lung Neoplasms Antibodies  >1 publications with GALR1 and Lung Neoplasms

Organs/Tissues associated with anti-GALR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >107 publications with GALR1 and Brain
 Nerve Antibodies  >33 publications with GALR1 and Nerve
 Prostate Antibodies  >2 publications with GALR1 and Prostate
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