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SLCO1B1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS858137

MBS858137 is an antibody targeting SLCO1B1. Also known as SLCO1B1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLCO1B1, Antibody
Full Product Name
SLCO1B1 Antibody
Product Gene Name
Product Synonym Names
Solute carrier family 21 member 6; Sodium-independent organic anion-transporting polypeptide 2; OATP 2; Liver-specific organic anion transporter 1; LST-1; OATP-C
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
SLCO1B1 antibody detects endogenous levels of total SLCO1B1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
76,449 Da
OMIM
237450
3D Structure
ModBase 3D Structure for Q9Y6L6
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human SLCO1B1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SLCO1B1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SLCO1B1 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-SLCO1B1 antibody

Western blot analysis of extracts from COLO205 and Jurkat cells, using SLCO1B1 antibody.
Anti-SLCO1B1 Antibody – Cat# MBS858137

Product References and Citations for anti-SLCO1B1 antibody

Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999). Keppler D., J. Biol. Chem. 275:23161-23168(2000). Venter J.C., Submitted (JUL-2005).

Other Notes

Small volumes of anti-SLCO1B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLCO1B1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
solute carrier organic anion transporter family member 1B1
NCBI Official Synonym Full Names
solute carrier organic anion transporter family member 1B1
NCBI Official Symbol
SLCO1B1
NCBI Official Synonym Symbols
LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6
UniProt Protein Name
Solute carrier organic anion transporter family member 1B1
UniProt Synonym Protein Names
Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solute carrier family 21 member 6
UniProt Gene Name
SLCO1B1
UniProt Synonym Gene Names
LST1; OATP1B1; OATP2; OATPC; SLC21A6; LST-1; OATP-2
NCBI Protein Information
solute carrier organic anion transporter family member 1B1

NCBI Summary for SLCO1B1

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]
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UniProt Comments for SLCO1B1

Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SLCO1B1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >137 publications with SLCO1B1 and Liver
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