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DNA Polymerase Lambda (POLL) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS858271

MBS858271 is an antibody targeting POLL. Also known as DNA Polymerase lambda Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA Polymerase lambda (POLL), Antibody
Full Product Name
DNA Polymerase lambda Antibody
Product Gene Name
Product Synonym Names
DNA polymerase lambda; EC 2.7.7.7; EC 4.2.99.-; Pol Lambda; DNA polymerase kappa; DNA polymerase beta-2; Pol beta2; POLL
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
DNA Polymerase lambda antibody detects endogenous levels of total DNA Polymerase lambda protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
33,839 Da
OMIM
606343
3D Structure
ModBase 3D Structure for Q9UGP5
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DNA Polymerase lambda.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-POLL antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-POLL antibody
WB: 1:500~1:1000
ELISA: 1:5000

Western Blot (WB) of anti-POLL antibody

Western blot analysis of extracts from 293 cells, using DNA Polymerase lambda antibody.
Anti-POLL Antibody – Cat# MBS858271

Product References and Citations for anti-POLL antibody

Aoufouchi S., Nucleic Acids Res. 28:3684-3693(2000). Nagasawa K.I., J. Biol. Chem. 275:31233-31238(2000). Ota T., Nat. Genet. 36:40-45(2004).

Other Notes

Small volumes of anti-POLL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for POLL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA polymerase lambda isoform a
NCBI Official Synonym Full Names
DNA polymerase lambda
NCBI Official Symbol
POLL
NCBI Official Synonym Symbols
BETAN; POLKAPPA
UniProt Protein Name
DNA polymerase lambda
UniProt Synonym Protein Names
DNA polymerase beta-2
Protein Family
UniProt Gene Name
POLL
UniProt Synonym Gene Names
Pol beta2
NCBI Protein Information
DNA polymerase lambda

NCBI Summary for POLL

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]
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UniProt Comments for POLL

DNA polymerase that functions in several pathways of DNA repair (PubMed:11457865, PubMed:19806195, PubMed:20693240). Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA (PubMed:11457865, PubMed:19806195). Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240). Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195). Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (PubMed:11457865, PubMed:19806195).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-POLL antibody

 Reference Product  PubMed Publications
 PCNA antibody  >1 publications with POLL and PCNA
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