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SOX9 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS858580

MBS858580 is an antibody targeting SOX9. Also known as SOX9 (Ab-181) Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SOX9, Antibody
Full Product Name
SOX9 (Ab-181) Antibody
Product Gene Name
Product Synonym Names
SRY sex determining region Y-box 9 protein; SRY-box containing gene 9; Sox-9; transcription factor SOX-9
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
SOX-9 (Ab-181) antibody detects endogenous levels of total SOX-9 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
56,137 Da
OMIM
114290
3D Structure
ModBase 3D Structure for P48436
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human SOX-9 around the phosphorylation site of serine 181 (R-K-SP-V-K).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SOX9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-SOX9 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000

Testing Data of anti-SOX9 antibody

Peptide-+
Anti-SOX9 Antibody – Cat# MBS858580

Immunohistochemistry (IHC) of anti-SOX9 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using SOX-9 (Ab-181) antibody. Western blot analysis of extracts from 293 cells, treated with PBS (60mins), using SOX-9 (Ab-181) antibody.
Anti-SOX9 Antibody, Immunohistochemistry (IHC) – Cat# MBS858580

Immunofluorescence (IF) of anti-SOX9 antibody

Peptide-+ Immunofluorescence analysis of A549 cells, using SOX-9 (Ab-181) antibody.
Anti-SOX9 Antibody, Immunofluorescence (IF) – Cat# MBS858580

Product References and Citations for anti-SOX9 antibody

E. Kolettas, Rheumatology, Oct 2001; 40: 1146-1156. Céline J. Guigon, Endocrinology, Jul 2005; 146: 2992-3004. Andrea S. Cupp, Biol Reprod, Jun 2003; 68: 2033. Sang-Gu Hwang, J. Biol. Chem., Aug 2005; 280: 29780-29787.

Other Notes

Small volumes of anti-SOX9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transcription factor SOX-9
NCBI Official Synonym Full Names
SRY-box 9
NCBI Official Symbol
SOX9
NCBI Official Synonym Symbols
CMD1; SRA1; CMPD1; SRXX2; SRXY10
UniProt Protein Name
Transcription factor SOX-9
Protein Family
UniProt Gene Name
SOX9
NCBI Protein Information
transcription factor SOX-9

NCBI Summary for SOX9

The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]
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UniProt Comments for SOX9

Transcriptional regulator (PubMed:24038782). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (). Plays a role in chondrocyte differentiation (). Important for normal skeletal development (PubMed:24038782).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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