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CARD11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS858705

Rabbit polyclonal CARD11 (1) antibody was raised against a recombinated human CARD11 protein 772-940aa (BC111719). More details

$430 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CARD11, Polyclonal Antibody
Full Product Name
CARD11 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3.
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Molecular Weight
133,284 Da
OMIM
607210
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CARD11 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CARD11 antibody
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500

Testing Data of anti-CARD11 antibody

Rabbit Anti-CARD11 Polyclonal Antibody – Cat# MBS858705

Testing Data of anti-CARD11 antibody

Rabbit Anti-CARD11 Polyclonal Antibody, Testing Data – Cat# MBS858705

Product References and Citations for anti-CARD11 antibody

(1) Liu, Y., Song, R., Gao, Y., et al. Protein kinase C-delta negatively regulates T cell receptor-induced NF-kappaB activation by inhibiting the assembly of CARMA1 signalosome. J. Biol. Chem. 287 (24), 20081-20087 (2012).

Other Notes

Small volumes of anti-CARD11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CARD11 purchase

MBS858705 is an antibody targeting CARD11. Also known as CARD11 Antibody. Reactive in Human
Predicted: Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CARD11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens caspase recruitment domain family, member 11, mRNA
NCBI Official Synonym Full Names
caspase recruitment domain family member 11
NCBI Official Symbol
CARD11
NCBI Official Synonym Symbols
PPBL; BENTA; BIMP3; IMD11; CARMA1; IMD11A
UniProt Protein Name
Caspase recruitment domain-containing protein 11
UniProt Synonym Protein Names
CARD-containing MAGUK protein 1; Carma 1
UniProt Gene Name
CARD11
UniProt Synonym Gene Names
; Carma 1
NCBI Protein Information
caspase recruitment domain-containing protein 11

NCBI Summary for CARD11

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
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UniProt Comments for CARD11

Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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