• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IL-7R/CD127 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859375

MBS859375 is an antibody targeting IL-7R/CD127. Also known as IL-7R/CD127 (Phospho-Tyr449) Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-7R/CD127, Antibody
Full Product Name
IL-7R/CD127 (Phospho-Tyr449) Antibody
Product Gene Name
Product Synonym Names
CD127 antigen; CDw127; IL-7R alpha; IL7RA; interleukin-7 receptor alpha chain
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
IL-7R/CD127 (Phospho-Tyr449) antibody detects endogenous levels of IL-7R/CD127 only when phosphorylated at tyrosine 449.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
28,724 Da
OMIM
146661
3D Structure
ModBase 3D Structure for P16871
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human IL-7R/CD127 around the phosphorylation site of tyrosine 449 (E-A-YP-V-T).
All Sites
Human: Tyr449
Mouse: Tyr449
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IL-7R/CD127 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-IL-7R/CD127 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:5000

Western Blot (WB) of anti-IL-7R/CD127 antibody

P-peptide-+ Western blot analysis of extracts from HeLa cells, using IL-7R/CD127 (Phospho-Tyr449) antibody. Immunofluorescence analysis of HUVEC cells, using IL-7R/CD127 (Phospho-Tyr449) antibody.
Anti-IL-7R/CD127 Antibody, Western Blot (WB) – Cat# MBS859375

Product References and Citations for anti-IL-7R/CD127 antibody

D Benjamin, J. Immunol., May 1994; 152: 4749. TH Page, J. Immunol., Nov 1993; 151: 4753. Kohtaro Fujihashi, PNAS, Apr 1996; 93: 3613.

Other Notes

Small volumes of anti-IL-7R/CD127 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-7R/CD127. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-7 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 7 receptor
NCBI Official Symbol
IL7R
NCBI Official Synonym Symbols
ILRA; CD127; IL7RA; CDW127; IL-7R-alpha
UniProt Protein Name
Interleukin-7 receptor subunit alpha
UniProt Synonym Protein Names
CDw127; CD_antigen: CD127
UniProt Gene Name
IL7R
UniProt Synonym Gene Names
IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA
NCBI Protein Information
interleukin-7 receptor subunit alpha

NCBI Summary for IL-7R/CD127

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
Show more

UniProt Comments for IL-7R/CD127

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000