• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

KIF2C Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859545

MBS859545 is an antibody targeting KIF2C. Also known as KIF2C (Phospho-Ser95) Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KIF2C, Antibody
Full Product Name
KIF2C (Phospho-Ser95) Antibody
Product Gene Name
Product Synonym Names
KF2C; KIF2C; KNSL6; Kinesin-like protein 6; Kinesin-like protein KIF2C; Mitotic centromere-associated kinesin
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
KIF2C (Phospho-Ser95) antibody detects endogenous levels of KIF2C only when phosphorylated at serine 95.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
75,561 Da
OMIM
604538
3D Structure
ModBase 3D Structure for Q99661
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human KIF2C around the phosphorylation site of serine 95 (R-R-SP-V-N).
All Sites
Human: Ser95
Mouse: Ser92
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KIF2C antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-KIF2C antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-KIF2C antibody

Anti-KIF2C Antibody – Cat# MBS859545

Western Blot (WB) of anti-KIF2C antibody

P-peptide-+ Western blot analysis of extracts from HeLa cells, treated with TNF (10ng/ml, 30mins), using KIF2C (Phospho-Ser95) antibody. Immunofluorescence analysis of A549 cells, using KIF2C (Phospho-Ser95) antibody.
Anti-KIF2C Antibody, Western Blot (WB) – Cat# MBS859545

Product References and Citations for anti-KIF2C antibody

Kim I.-G., Biochim. Biophys. Acta 1359:181-186(1997). Cheng L.J.; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-KIF2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF2C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kinesin-like protein KIF2C isoform 2
NCBI Official Synonym Full Names
kinesin family member 2C
NCBI Official Symbol
KIF2C
NCBI Official Synonym Symbols
MCAK; CT139; KNSL6
UniProt Protein Name
Kinesin-like protein KIF2C
UniProt Synonym Protein Names
Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK
Protein Family
UniProt Gene Name
KIF2C
UniProt Synonym Gene Names
KNSL6; MCAK
NCBI Protein Information
kinesin-like protein KIF2C

NCBI Summary for KIF2C

This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Show more

UniProt Comments for KIF2C

In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108).
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000