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CD88/C5aR Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859654

MBS859654 is an antibody targeting CD88/C5aR. Also known as CD88/C5aR (Ab-338) Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD88/C5aR, Antibody
Full Product Name
CD88/C5aR (Ab-338) Antibody
Product Gene Name
Product Synonym Names
C5AR; C5AR1; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; CD88 antigen
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1mg/ml (lot specific)
Specificity
CD88/C5aR (Ab-338) antibody detects endogenous levels of total CD88/C5aR protein.
Preparation and Storage
Store at-20 degree C for 1 year.
OMIM
113995
3D Structure
ModBase 3D Structure for P21730
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human CD88/C5aR around the phosphorylation site of serine 338(T-R-SP-T-V).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD88/C5aR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CD88/C5aR antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000

Immunohistochemistry (IHC) of anti-CD88/C5aR antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using CD88/C5aR (Ab-338) antibody.
Anti-CD88/C5aR Antibody – Cat# MBS859654

Western Blot (WB) of anti-CD88/C5aR antibody

Western blot analysis of extracts from HeLa cells, treated with PMA (125ng/ml, 30mins), using CD88/C5aR (Ab-338) antibody.
Anti-CD88/C5aR Antibody, Western Blot (WB) – Cat# MBS859654

Immunofluorescence (IF) of anti-CD88/C5aR antibody

Immunofluorescence analysis of HeLa cells, using CD88/C5aR (Ab-338) antibody.
Anti-CD88/C5aR Antibody, Immunofluorescence (IF) – Cat# MBS859654

Product References and Citations for anti-CD88/C5aR antibody

W Fureder, J. Immunol., Sep 1995; 155: 3152. T Werfel, J. Immunol., Aug 1996; 157: 1729. Anthony A. Floreani, J. Immunol., May 1998; 160: 5073. M Burg, J. Immunol., Dec 1996; 157: 5574.

Other Notes

Small volumes of anti-CD88/C5aR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD88/C5aR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C5a anaphylatoxin chemotactic receptor 1
NCBI Official Synonym Full Names
complement C5a receptor 1
NCBI Official Symbol
C5AR1
NCBI Official Synonym Symbols
C5A; C5AR; C5R1; CD88
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor 1
UniProt Synonym Protein Names
C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88
UniProt Gene Name
C5AR1
UniProt Synonym Gene Names
C5AR; C5R1; C5a-R; C5aR
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor 1

UniProt Comments for CD88/C5aR

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD88/C5aR antibody

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