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Interferon-Gamma Receptor Alpha Chain (INGR1) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859729

MBS859729 is an antibody targeting INGR1. Also known as Interferon-gamma Receptor alpha chain (Ab-457) Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interferon-gamma Receptor alpha chain (INGR1), Antibody
Full Product Name
Interferon-gamma Receptor alpha chain (Ab-457) Antibody
Product Gene Name
Product Synonym Names
CD119 antigen; CDw119; IFN-gamma-R1; INGR; Interferon-gamma receptor alpha chain precursor
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Interferon-gamma Receptor alpha chain (Ab-457) antibody detects endogenous levels of total Interferon-gamma Receptor α chain protein.
Preparation and Storage
Store at-20°C/1 year.
OMIM
107470
3D Structure
ModBase 3D Structure for P15260
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human Interferon-γ Receptor α chain around the phosphorylation site of tyreonine 457 (G-YP-D-K-P).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-INGR1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-INGR1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:40000

Immunohistochemistry of anti-INGR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Interferon-γ Receptor α chain (Ab-457) antibody.
Rabbit Anti-INGR1 Antibody – Cat# MBS859729

Western Blot of anti-INGR1 antibody

Western blot analysis of extracts from COS7 cells, using Interferon-γ Receptor α chain (Ab-457) antibody.
Rabbit Anti-INGR1 Antibody, Western Blot – Cat# MBS859729

Immunofluorescence (IF) of anti-INGR1 antibody

Immunofluorescence analysis of HepG2 cells, using Interferon-γ Receptor α chain (Ab-457) antibody.
Rabbit Anti-INGR1 Antibody, Immunofluorescence (IF) – Cat# MBS859729

Product References and Citations for anti-INGR1 antibody

Mungall A.J., Nature 425:805-811(2003). Stueber D., Biochemistry 32:2423-2430(1993). Walter M.R., Nature 376:230-235(1995). Thiel D.J., Structure 8:927-936(2000).

Other Notes

Small volumes of anti-INGR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INGR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon gamma receptor 1
NCBI Official Synonym Full Names
interferon gamma receptor 1
NCBI Official Symbol
IFNGR1
NCBI Official Synonym Symbols
CD119; IFNGR; IMD27A; IMD27B
UniProt Protein Name
Interferon gamma receptor 1
UniProt Synonym Protein Names
CDw119; Interferon gamma receptor alpha-chain
UniProt Gene Name
IFNGR1
UniProt Synonym Gene Names
IFN-gamma-R-alpha
NCBI Protein Information
interferon gamma receptor 1

NCBI Summary for INGR1

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
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UniProt Comments for INGR1

Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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