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n-NOS Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859762

MBS859762 is an antibody targeting n-NOS. Also known as n-NOS (Phospho-Ser852) Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
n-NOS, Antibody
Full Product Name
n-NOS (Phospho-Ser852) Antibody
Product Gene Name
anti-n-NOS antibody
Product Synonym Names
BNOS; Constitutive NOS; EC 1.14.13.39; N-NOS; NC-NOS; NOS; type I; NOS1; Neuronal NOS; Nitric-oxide synthase; brain; bNOS
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
n-NOS (Phospho-Ser852) antibody detects endogenous levels of n-NOS only when phosphorylated at serine 847.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
164,430 Da
3D Structure
ModBase 3D Structure for P29476
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human n-NOS around the phosphorylation site of serine 847 (F-N-SP-V-S).
All Sites
Human: Ser852
Mouse: Ser847
Rat: Ser847

Product Categories/Family for anti-n-NOS antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-n-NOS antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-n-NOS antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-n-NOS antibody

P-peptide-+
Anti-n-NOS Antibody – Cat# MBS859762

Immunohistochemistry (IHC) of anti-n-NOS antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using n-NOS (Phospho-Ser852) antibody. Western blot analysis of extracts from A549 cells, using n-NOS (Phospho-Ser852) antibody.
Anti-n-NOS Antibody, Immunohistochemistry (IHC) – Cat# MBS859762

Immunofluorescence (IF) of anti-n-NOS antibody

P-peptide-+ Immunofluorescence analysis of HeLa cells, using n-NOS (Phospho-Ser852) antibody.
Anti-n-NOS Antibody, Immunofluorescence (IF) – Cat# MBS859762

Product References and Citations for anti-n-NOS antibody

George D. Webb, J. Thorac. Cardiovasc. Surg., Nov 2006; 132: 1131-1136. Montserrat García-Vitoria, J. Histochem. Cytochem., Aug 2000; 48: 1111. Peter J. Reiser, J Appl Physiol, Apr 1997; 82: 1250. VL Dawson, J. Neurosci., Apr 1996; 16: 2479.

Other Notes

Small volumes of anti-n-NOS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for n-NOS. It may not necessarily be applicable to this product.

NCBI GI #
16258811
NCBI GeneID
24598
NCBI Accession #
NP_434686.1
UniProt Primary Accession #
P29476
UniProt Secondary Accession #
P70594
UniProt Related Accession #
P29476
GenBank Nucleotide #
NM_052799.1
NCBI Official Full Name
nitric oxide synthase, brain
NCBI Official Synonym Full Names
nitric oxide synthase 1
NCBI Official Symbol
Nos1
NCBI Official Synonym Symbols
bNOS
UniProt Protein Name
Nitric oxide synthase, brain
UniProt Synonym Protein Names
BNOS; Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1
Protein Family
Nanos
UniProt Gene Name
Nos1
UniProt Synonym Gene Names
Bnos; N-NOS; nNOS
NCBI Protein Information
nitric oxide synthase, brain

NCBI Summary for n-NOS

enzyme that catalyzes the production of nitric oxide [RGD, Feb 2006]

UniProt Comments for n-NOS

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
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Research Articles on n-NOS

1. we demonstrated a significant upregulation of nNOS expression, accompanied by significant increases in NOS activity and NO production, in the brain of rats exposed to simulated weightlessness.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-n-NOS antibody

 Reference Product  PubMed Publications
 Cav1 antibody  >7 publications with n-NOS and Cav1
 Grin2b antibody  >5 publications with n-NOS and Grin2b
 Dlg4 antibody  >2 publications with n-NOS and Dlg4
 Ass1 antibody  >1 publications with n-NOS and Ass1
 Dlg1 antibody  >1 publications with n-NOS and Dlg1

Pathways associated with anti-n-NOS antibody

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Diseases associated with anti-n-NOS antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >541 publications with n-NOS and Nervous System Diseases
 Brain Diseases Antibodies  >294 publications with n-NOS and Brain Diseases
 Mental Disorders Antibodies  >187 publications with n-NOS and Mental Disorders
 Hypertension Antibodies  >172 publications with n-NOS and Hypertension
 Inflammation Antibodies  >153 publications with n-NOS and Inflammation
 Heart Diseases Antibodies  >108 publications with n-NOS and Heart Diseases
 Pain Antibodies  >105 publications with n-NOS and Pain
 Anoxia Antibodies  >101 publications with n-NOS and Anoxia
 Kidney Diseases Antibodies  >61 publications with n-NOS and Kidney Diseases
 Schizophrenia Antibodies  >55 publications with n-NOS and Schizophrenia

Organs/Tissues associated with anti-n-NOS antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >532 publications with n-NOS and Muscle
 Testis Antibodies  >7 publications with n-NOS and Testis
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