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IL31RA Antibody – Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859822

Rabbit polyclonal IL31RA (1) antibody was raised against a recombinate human IL31RA protein 91-378aa (BC110490). More details

$430 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL31RA, Polyclonal Antibody
Full Product Name
IL31RA Antibody
Product Gene Name
Clonality
Polyclonal
Species Reactivity
Human
Predicted: Mouse, Rat
Not yet tested in other species.
Form/Format
IL31RA antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Store at +4 ° C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark.
OMIM
609510
Source
Rabbit
Conjugation
AF555
Reconstitution
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20ºC after reconstitution.
Avoid repeated freeze/defrost cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IL31RA antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-IL31RA antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Testing Data of anti-IL31RA antibody

Anti-IL31RA Polyclonal Antibody – Cat# MBS859822

Testing Data of anti-IL31RA antibody

Anti-IL31RA Polyclonal Antibody, Testing Data – Cat# MBS859822

Product References and Citations for anti-IL31RA antibody

(1) Feld, M., Shpacovitch, V.M., Fastrich, M., et al. Interferon-gamma induces upregulation and activation of the interleukin-31 receptor in human dermal microvascular endothelial cells. Exp. Dermatol. 19 (10), 921-923 (2010).

Other Notes

Small volumes of anti-IL31RA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL31RA purchase

MBS859822 is an antibody targeting IL31RA. Also known as IL31RA Antibody. Reactive in Human
Predicted: Mouse, Rat
Not yet tested in other species..

Additional Details

NCBI/Uniprot data below describe general gene information for IL31RA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens interleukin 31 receptor A, mRNA
NCBI Official Synonym Full Names
interleukin 31 receptor A
NCBI Official Symbol
IL31RA
NCBI Official Synonym Symbols
CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384
UniProt Protein Name
Interleukin-31 receptor subunit alpha
UniProt Synonym Protein Names
Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17
UniProt Gene Name
IL31RA
UniProt Synonym Gene Names
CRL3; GPL; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; hGLM-R; Gp130-like receptor
NCBI Protein Information
interleukin-31 receptor subunit alpha

NCBI Summary for IL31RA

The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
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UniProt Comments for IL31RA

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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