Chemokine C-Motif Ligand 2 (XCL2) ELISA Kit for Hamster

Name: Hamster XCL2 ELISA Kit; Chemokine C-Motif Ligand 2; MyBioSource
Brand: MyBioSource
SKU: MBS088144
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS088144

MBS088144 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chemokine C-Motif Ligand 2 (XCL2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Chemokine C-Motif Ligand 2 (XCL2), ELISA Kit

Full Product Name

Hamster Chemokine C-Motif Ligand 2 ELISA Kit

Product Gene Name

XCL2 elisa kit

Species Reactivity

Hamster

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

38,508 Da

OMIM

600552

3D Structure

ModBase 3D Structure for P46094

Other Notes

Small volumes of XCL2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for XCL2. It may not necessarily be applicable to this product.

NCBI GI #

66932941

NCBI GeneID

2829

NCBI Accession #

NP_001019815.1

UniProt Primary Accession #

P46094

UniProt Related Accession #

P46094

GenBank Nucleotide #

NM_001024644.1

NCBI Official Full Name

chemokine XC receptor 1

NCBI Official Synonym Full Names

chemokine (C motif) receptor 1

NCBI Official Symbol

XCR1

NCBI Official Synonym Symbols

GPR5; CCXCR1

UniProt Protein Name

Chemokine XC receptor 1

UniProt Synonym Protein Names

G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1

Protein Family

Cytokine

UniProt Gene Name

XCR1

UniProt Synonym Gene Names

CCXCR1; GPR5

UniProt Entry Name

XCR1_HUMAN

NCBI Protein Information

chemokine XC receptor 1; lymphotactin receptor; XC chemokine receptor 1; G protein-coupled receptor 5; G-protein coupled receptor 5; chemokine (C motif) XC receptor 1

NCBI Summary for XCL2

The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for XCL2

XCR1: Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: chemokine receptor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; release of sequestered calcium ion into cytosol; inflammatory response; chemotaxis

Research Articles on XCL2

1. XCR1 is expressed early during the course of tumorigenic transformation and contributes towards increased cell migration and proliferation, which can facilitate the prometastatic behavior of epithelial ovarian cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with XCL2 elisa kit

Reference Product	PubMed Publications
XCL1 elisa kit	>28 publications with XCL2 and XCL1
CCL3 elisa kit	>1 publications with XCL2 and CCL3
XCL2 elisa kit	>1 publications with XCL2 and XCL2

Pathways associated with XCL2 elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with XCL2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>14 publications with XCL2 and Neoplasms
Inflammation Antibodies	>8 publications with XCL2 and Inflammation
Liver Neoplasms Antibodies	>3 publications with XCL2 and Liver Neoplasms
Lung Diseases Antibodies	>3 publications with XCL2 and Lung Diseases
Respiratory Tract Diseases Antibodies	>2 publications with XCL2 and Respiratory Tract Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with XCL2 and Carcinoma, Hepatocellular
Heart Diseases Antibodies	>1 publications with XCL2 and Heart Diseases
Necrosis Antibodies	>1 publications with XCL2 and Necrosis
Lung Neoplasms Antibodies	>1 publications with XCL2 and Lung Neoplasms
Respiratory Hypersensitivity Antibodies	>1 publications with XCL2 and Respiratory Hypersensitivity

Organs/Tissues associated with XCL2 elisa kit

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>3 publications with XCL2 and Placenta