Thymic Stromal Lymphopoietin (TSLP) ELISA Kit for Canine

Name: Canine TSLP ELISA Kit; Thymic Stromal Lymphopoietin; MyBioSource
Brand: MyBioSource
SKU: MBS008986
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS008986

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of TSLP (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Thymic Stromal Lymphopoietin (TSLP), ELISA Kit

Full Product Name

Canine Thymic Stromal Lymphopoietin ELISA Kit

Product Gene Name

TSLP elisa kit

Species Reactivity

Canine

Assay Type

Quantitative Sandwich

Detection Range

3.12pg/ml-100pg/ml

Sensitivity

1.0pg/ml

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

18,141 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (110405778..110413722). Location: 5q22.1

OMIM

607003

3D Structure

ModBase 3D Structure for Q969D9

Other Notes

Small volumes of TSLP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TSLP purchase

MBS008986 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thymic Stromal Lymphopoietin (TSLP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TSLP. The ELISA analytical biochemical technique of the MBS008986 kit is based on TSLP antibody-TSLP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TSLP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TSLP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TSLP. It may not necessarily be applicable to this product.

NCBI GI #

190886449

NCBI GeneID

85480

NCBI Accession #

NP_612561.2

UniProt Primary Accession #

Q969D9

UniProt Secondary Accession #

Q8IW99

UniProt Related Accession #

Q969D9

GenBank Nucleotide #

NM_138551.4

NCBI Official Full Name

thymic stromal lymphopoietin isoform 2

NCBI Official Synonym Full Names

thymic stromal lymphopoietin

NCBI Official Symbol

TSLP

UniProt Protein Name

Thymic stromal lymphopoietin

Protein Family

Thymic stromal lymphopoietin

UniProt Gene Name

TSLP

UniProt Entry Name

TSLP_HUMAN

NCBI Protein Information

thymic stromal lymphopoietin

NCBI Summary for TSLP

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

UniProt Comments for TSLP

TSLP: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q22.1

Cellular Component: extracellular space

Molecular Function: cytokine activity

Research Articles on TSLP

1. This study suggests that SNPs in TSLP gene may exert a gender and/or nasal polyposis-dependent risk for development of CRS in Chinese subjects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TSLP elisa kit

Reference Product	PubMed Publications
CRLF2 elisa kit	>49 publications with TSLP and CRLF2
TNFSF4 elisa kit	>29 publications with TSLP and TNFSF4
IL13 elisa kit	>26 publications with TSLP and IL13
FOXP3 elisa kit	>22 publications with TSLP and FOXP3
CCL17 elisa kit	>14 publications with TSLP and CCL17
IL7R elisa kit	>5 publications with TSLP and IL7R
IL4 elisa kit	>5 publications with TSLP and IL4
IL9 elisa kit	>1 publications with TSLP and IL9

Pathways associated with TSLP elisa kit

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
TSLP Signaling Pathway antibodies	TSLP Signaling Pathway Diagram

Diseases associated with TSLP elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>220 publications with TSLP and Inflammation
Asthma Antibodies	>154 publications with TSLP and Asthma
Dermatitis, Atopic Antibodies	>119 publications with TSLP and Dermatitis, Atopic
Lung Diseases Antibodies	>99 publications with TSLP and Lung Diseases
Necrosis Antibodies	>50 publications with TSLP and Necrosis
Disease Models, Animal Antibodies	>44 publications with TSLP and Disease Models, Animal
Drug Hypersensitivity Antibodies	>13 publications with TSLP and Drug Hypersensitivity
Hyperplasia Antibodies	>12 publications with TSLP and Hyperplasia
Glomerulonephritis, Membranoproliferative Antibodies	>8 publications with TSLP and Glomerulonephritis, Membranoproliferative
Cardiovascular Diseases Antibodies	>7 publications with TSLP and Cardiovascular Diseases

Organs/Tissues associated with TSLP elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>115 publications with TSLP and Skin
Lung Antibodies	>104 publications with TSLP and Lung
Bone Marrow Antibodies	>22 publications with TSLP and Bone Marrow
Eye Antibodies	>7 publications with TSLP and Eye
Connective Tissue Antibodies	>1 publications with TSLP and Connective Tissue
Thyroid Antibodies	>1 publications with TSLP and Thyroid
Brain Antibodies	>1 publications with TSLP and Brain