Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) ELISA Kit for Mouse

Name: Mouse METRNL ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS901036
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS901036

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for METRNL has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any METRNL present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

meteorin, glial cell differentiation regulator-like (METRNL), ELISA Kit

Full Product Name

Mouse Meteorin-like protein, METRNL ELISA Kit

Product Gene Name

METRNL elisa kit

Product Synonym Names

Mouse Meteorin-like protein (METRNL) ELISA kit; MGC99788; ; meteorin; glial cell differentiation regulator-like

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates, Cell lysates

Detection Range

31.25 pg/ml -2000 pg/ml.

Sensitivity

The minimum detectable dose of mouse METRNL is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

Specificity

This assay has high sensitivity and excellent specificity for detection of mouse METRNL. No significant cross-reactivity or interference between mouse METRNL and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

34,530 Da

3D Structure

ModBase 3D Structure for Q8VE43

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of METRNL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for METRNL purchase

MBS901036 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the meteorin, glial cell differentiation regulator-like (METRNL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing METRNL. The ELISA analytical biochemical technique of the MBS901036 kit is based on METRNL antibody-METRNL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect METRNL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, METRNL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for METRNL. It may not necessarily be applicable to this product.

NCBI GI #

21450153

NCBI GeneID

210029

NCBI Accession #

NP_659046.1

UniProt Primary Accession #

Q8VE43

UniProt Secondary Accession #

Q8R1J2

UniProt Related Accession #

Q8VE43

GenBank Nucleotide #

NM_144797.3

NCBI Official Full Name

meteorin-like protein

NCBI Official Synonym Full Names

meteorin, glial cell differentiation regulator-like

NCBI Official Symbol

Metrnl

NCBI Official Synonym Symbols

BC019776; 9430048M07Rik

UniProt Protein Name

Meteorin-like protein

UniProt Synonym Protein Names

Subfatin

Protein Family

Meteorin-like protein

UniProt Gene Name

Metrnl

UniProt Entry Name

METRL_MOUSE

NCBI Protein Information

meteorin-like protein; cometin

UniProt Comments for METRNL

METRNL: Belongs to the meteorin family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: hormone activity

Biological Process: fat cell differentiation; response to muscle activity; negative regulation of inflammatory response; brown fat cell differentiation; response to cold

Research Articles on METRNL

1. Study reports the identification of meteorin-like (Metrnl), a circulating factor that is induced in muscle after exercise and in adipose tissue upon cold exposure; increasing circulating levels of Metrnl stimulates energy expenditure and improves glucose tolerance and the expression of genes associated with beige fat thermogenesis and anti-inflammatory cytokines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with METRNL elisa kit

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>1 publications with METRNL and Liver Diseases
Inflammation Antibodies	>1 publications with METRNL and Inflammation

Organs/Tissues associated with METRNL elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with METRNL and Skin