Epiregulin (EREG) ELISA Kit for Human

Name: Human EREG ELISA Kit; Epiregulin; MyBioSource
Brand: MyBioSource
SKU: MBS904261
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS904261

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for EREG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any EREG present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

epiregulin (EREG), ELISA Kit

Full Product Name

Human epiregulin, EREG ELISA Kit

Product Gene Name

EREG elisa kit

Product Synonym Names

Human epiregulin (EREG) ELISA kit; ER; ; epiregulin

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, tissue homogenates

Detection Range

15.6 pg/ml-1000 pg/ml

Sensitivity

< 3.9 pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of human EREG. No significant cross-reactivity or interference between human EREG and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

19,044 Da

OMIM

602061

3D Structure

ModBase 3D Structure for O14944

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EREG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EREG purchase

MBS904261 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the epiregulin (EREG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EREG. The ELISA analytical biochemical technique of the MBS904261 kit is based on EREG antibody-EREG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EREG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EREG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for EREG. It may not necessarily be applicable to this product.

NCBI GI #

4557567

NCBI GeneID

2069

NCBI Accession #

NP_001423.1

UniProt Primary Accession #

O14944

UniProt Secondary Accession #

Q6FH69; B2RC66

UniProt Related Accession #

O14944

GenBank Nucleotide #

NM_001432.2

NCBI Official Full Name

proepiregulin preproprotein

NCBI Official Synonym Full Names

epiregulin

NCBI Official Symbol

EREG

NCBI Official Synonym Symbols

UniProt Protein Name

Proepiregulin

Protein Family

Proepiregulin

UniProt Gene Name

EREG

UniProt Synonym Gene Names

EPR

UniProt Entry Name

EREG_HUMAN

NCBI Protein Information

proepiregulin

NCBI Summary for EREG

Epiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. [provided by RefSeq, Jul 2008]

UniProt Comments for EREG

Epiregulin: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; integral to plasma membrane; extracellular region

Molecular Function: protein binding; growth factor activity; epidermal growth factor receptor binding

Biological Process: response to peptide hormone stimulus; nerve growth factor receptor signaling pathway; wound healing; activation of MAPK activity; positive regulation of interleukin-6 biosynthetic process; positive regulation of smooth muscle cell proliferation; female meiosis; negative regulation of smooth muscle cell differentiation; negative regulation of cell proliferation; primary follicle stage, oogenesis; positive regulation of fibroblast proliferation; positive regulation of epidermal growth factor receptor activity; cell-cell signaling; positive regulation of innate immune response; positive regulation of cell proliferation; ovarian cumulus expansion; angiogenesis; negative regulation of epithelial cell proliferation; positive regulation of cytokine production; epidermal growth factor receptor signaling pathway; anatomical structure morphogenesis; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; positive regulation of mitosis; cytokine and chemokine mediated signaling pathway; positive regulation of cytokine biosynthetic process; keratinocyte proliferation; luteinizing hormone signaling pathway; oocyte maturation; keratinocyte differentiation; ovulation; organ morphogenesis; positive regulation of protein kinase activity; mRNA transcription; innate immune response; negative regulation of transcription, DNA-dependent; positive regulation of DNA replication; positive regulation of phosphorylation

Research Articles on EREG

1. Epiregulin is a transcriptional target of TSC2 (tuberin).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EREG elisa kit

Reference Product	PubMed Publications
EGFR elisa kit	>22 publications with EREG and EGFR
ERBB4 elisa kit	>1 publications with EREG and ERBB4

Pathways associated with EREG elisa kit

Products by Pathway	Pathway Diagram
ErbB Receptor Signaling Network Pathway antibodies	ErbB Receptor Signaling Network Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
ErbB4 Signaling Events Pathway antibodies	ErbB4 Signaling Events Pathway Diagram
GRB2 Events In ERBB2 Signaling Pathway antibodies	GRB2 Events In ERBB2 Signaling Pathway Diagram
Nuclear Signaling By ERBB4 Pathway antibodies	Nuclear Signaling By ERBB4 Pathway Diagram
PI3K Events In ERBB2 Signaling Pathway antibodies	PI3K Events In ERBB2 Signaling Pathway Diagram
PI3K Events In ERBB4 Signaling Pathway antibodies	PI3K Events In ERBB4 Signaling Pathway Diagram
SHC1 Events In ERBB2 Signaling Pathway antibodies	SHC1 Events In ERBB2 Signaling Pathway Diagram

Diseases associated with EREG elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>22 publications with EREG and Neoplasms
Gastrointestinal Diseases Antibodies	>9 publications with EREG and Gastrointestinal Diseases
Gastrointestinal Neoplasms Antibodies	>8 publications with EREG and Gastrointestinal Neoplasms
Colorectal Neoplasms Antibodies	>8 publications with EREG and Colorectal Neoplasms
Carcinoma Antibodies	>7 publications with EREG and Carcinoma
Breast Neoplasms Antibodies	>6 publications with EREG and Breast Neoplasms
Liver Neoplasms Antibodies	>5 publications with EREG and Liver Neoplasms
Neoplasm Metastasis Antibodies	>5 publications with EREG and Neoplasm Metastasis
Drug Toxicity Antibodies	>4 publications with EREG and Drug Toxicity
Disease Models, Animal Antibodies	>4 publications with EREG and Disease Models, Animal

Organs/Tissues associated with EREG elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>7 publications with EREG and Blood
Lung Antibodies	>6 publications with EREG and Lung
Liver Antibodies	>6 publications with EREG and Liver
Skin Antibodies	>5 publications with EREG and Skin
Muscle Antibodies	>4 publications with EREG and Muscle
Lymph Node Antibodies	>1 publications with EREG and Lymph Node
Kidney Antibodies	>1 publications with EREG and Kidney
Intestine Antibodies	>1 publications with EREG and Intestine
Mouth Antibodies	>1 publications with EREG and Mouth