Hyaluronan Binding Protein 2 (HABP2) ELISA Kit for Human

Name: Human HABP2 ELISA Kit; Hyaluronan Binding Protein 2; MyBioSource
Brand: MyBioSource
SKU: MBS906566
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS906566

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for HABP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any HABP2 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

hyaluronan binding protein 2 (HABP2), ELISA Kit

Full Product Name

Human Hyaluronan-binding protein 2, HABP2 ELISA Kit

Product Gene Name

HABP2 elisa kit

Product Synonym Names

Human Hyaluronan-binding protein 2 (HABP2) ELISA kit; FSAP; HABP; HGFAL; PHBP; factor VII activating protein; hepatocyte growth factor activator-like protein; hyaluronic acid binding protein 2; plasma hyaluronan binding protein; hyaluronan binding protein 2

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, tissue homogenates

Detection Range

0.312 ng/ml-20 ng/ml

Sensitivity

< 0.078 ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of human HABP2. No significant cross-reactivity or interference between human HABP2 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

62,672 Da

OMIM

603924

3D Structure

ModBase 3D Structure for Q14520

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HABP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HABP2 purchase

MBS906566 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the hyaluronan binding protein 2 (HABP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HABP2. The ELISA analytical biochemical technique of the MBS906566 kit is based on HABP2 antibody-HABP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HABP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HABP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HABP2. It may not necessarily be applicable to this product.

NCBI GI #

295054188

NCBI GeneID

3026

NCBI Accession #

NP_001171131.1

UniProt Primary Accession #

Q14520

UniProt Secondary Accession #

O00663; A8K467; B7Z8U5; F5H5M6

UniProt Related Accession #

Q14520

GenBank Nucleotide #

NM_001177660.1

NCBI Official Full Name

hyaluronan-binding protein 2 isoform 2

NCBI Official Synonym Full Names

hyaluronan binding protein 2

NCBI Official Symbol

HABP2

NCBI Official Synonym Symbols

FSAP; HABP; PHBP; HGFAL

UniProt Protein Name

Hyaluronan-binding protein 2

UniProt Synonym Protein Names

Factor VII-activating protease; Factor seven-activating protease; FSAP; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding proteinCleaved into the following 4 chains:Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form

Protein Family

Hyaluronan-binding protein

UniProt Gene Name

HABP2

UniProt Synonym Gene Names

HGFAL; PHBP; FSAP

UniProt Entry Name

HABP2_HUMAN

NCBI Protein Information

hyaluronan-binding protein 2; factor VII activating protein; factor VII-activating protease; factor seven-activating protease; hyaluronic acid binding protein 2; plasma hyaluronan binding protein; plasma hyaluronan-binding protein; hepatocyte growth factor activator-like protein

NCBI Summary for HABP2

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

UniProt Comments for HABP2

HABP2: Cleaves the alpha-chain at multiple sites and the beta- chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro- urokinase) to the active two chain form. Activates coagulation factor VII. Belongs to the peptidase S1 family.

Protein type: Protease; Secreted, signal peptide; Cell adhesion; Motility/polarity/chemotaxis; Secreted; EC 3.4.21.-

Chromosomal Location of Human Ortholog: 10q25.3

Cellular Component: extracellular space; extracellular region

Molecular Function: glycosaminoglycan binding; serine-type endopeptidase activity

Biological Process: proteolysis; cell adhesion

Disease: Thrombophilia Due To Thrombin Defect; Thyroid Cancer, Nonmedullary, 5

Research Articles on HABP2

1. FSAP activates the NF-kappaB pathway and the associated downstream pro-inflammatory factors in monocytic cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HABP2 elisa kit

Reference Product	PubMed Publications
KNG1 elisa kit	>1 publications with HABP2 and KNG1

Diseases associated with HABP2 elisa kit

Disease Name	Pubmed Publications
Thrombosis Antibodies	>18 publications with HABP2 and Thrombosis
Atherosclerosis Antibodies	>7 publications with HABP2 and Atherosclerosis
Nervous System Diseases Antibodies	>6 publications with HABP2 and Nervous System Diseases
Brain Diseases Antibodies	>6 publications with HABP2 and Brain Diseases
Neoplasms Antibodies	>5 publications with HABP2 and Neoplasms
Fibrosis Antibodies	>5 publications with HABP2 and Fibrosis
Cerebrovascular Disorders Antibodies	>5 publications with HABP2 and Cerebrovascular Disorders
Thrombophilia Antibodies	>4 publications with HABP2 and Thrombophilia
Liver Diseases Antibodies	>3 publications with HABP2 and Liver Diseases
Lung Neoplasms Antibodies	>3 publications with HABP2 and Lung Neoplasms

Organs/Tissues associated with HABP2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>37 publications with HABP2 and Blood
Muscle Antibodies	>10 publications with HABP2 and Muscle
Lung Antibodies	>7 publications with HABP2 and Lung
Liver Antibodies	>6 publications with HABP2 and Liver
Heart Antibodies	>2 publications with HABP2 and Heart
Connective Tissue Antibodies	>1 publications with HABP2 and Connective Tissue
Embryonic Tissue Antibodies	>1 publications with HABP2 and Embryonic Tissue
Pancreas Antibodies	>1 publications with HABP2 and Pancreas
Kidney Antibodies	>1 publications with HABP2 and Kidney