Mouse SERPINA6 ELISA Kit – Cat# MBS908065

Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) ELISA Kit for Mouse

Name: Mouse SERPINA6 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS908065
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS908065

Principle of the Assay||This assay employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with goat-anti-rabbit antibody. Standards or samples are added to the appropriate microtiter plate wells… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) , member 6 (SERPINA6), ELISA Kit

Full Product Name

Mouse Corticosteroid-binding globulin, SERPINA6 ELISA Kit

Product Gene Name

SERPINA6 elisa kit

Product Synonym Names

Mouse Corticosteroid-binding globulin (SERPINA6) ELISA kit; CBG; corticosteroid binding globulin; serine (or cysteine) proteinase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 6; transcortin; serpin peptidase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 6

Species Reactivity

Mouse

Assay Type

Competitive

Samples

Serum, plasma.

Detection Range

0. 2 ug/ml -80 ug/ml.

Sensitivity

0.2 ug/ml.

Specificity

This assay has high sensitivity and excellent specificity for detection of mouse SERPINA6. No significant cross-reactivity or interference between mouse SERPINA6 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

44,769 Da

3D Structure

ModBase 3D Structure for Q06770

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SERPINA6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINA6 purchase

MBS908065 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 (SERPINA6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SERPINA6. The ELISA analytical biochemical technique of the MBS908065 kit is based on SERPINA6 antibody-SERPINA6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SERPINA6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SERPINA6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINA6. It may not necessarily be applicable to this product.

NCBI GI #

6680856

NCBI GeneID

12401

NCBI Accession #

NP_031644.1

UniProt Primary Accession #

Q06770

UniProt Related Accession #

Q06770

GenBank Nucleotide #

NM_007618.2

NCBI Official Full Name

corticosteroid-binding globulin

NCBI Official Synonym Full Names

serine (or cysteine) peptidase inhibitor, clade A, member 6

NCBI Official Symbol

Serpina6

NCBI Official Synonym Symbols

Cbg; AI265318; AV104445

UniProt Protein Name

Corticosteroid-binding globulin

UniProt Synonym Protein Names

Serpin A6; Transcortin

Protein Family

Corticosteroid-binding globulin

UniProt Gene Name

Serpina6

UniProt Synonym Gene Names

Cbg; CBG

UniProt Entry Name

CBG_MOUSE

NCBI Protein Information

corticosteroid-binding globulin; serpin A6; transcortin; corticosteroid binding globulin; serine (or cysteine) proteinase inhibitor, clade A, member 6

UniProt Comments for SERPINA6

SERPINA6: Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency). CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. Belongs to the serpin family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; lipid binding; steroid binding

Biological Process: glucocorticoid metabolic process; transport

Research Articles on SERPINA6

1. Data suggest fine control interaction between plasma CBG upregulation and stress-induced corticosterone (CORT) release in mouse model of psychological stress; CBG appears to function in maintaining dynamic equilibrium between CBG-bound/-unbound CORT.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with SERPINA6 elisa kit

Disease Name	Pubmed Publications
Fatigue Antibodies	>6 publications with SERPINA6 and Fatigue
Nervous System Diseases Antibodies	>4 publications with SERPINA6 and Nervous System Diseases
Pain Antibodies	>4 publications with SERPINA6 and Pain
Muscular Diseases Antibodies	>3 publications with SERPINA6 and Muscular Diseases
CORTICOSTEROID-BINDING GLOBULIN DEFICIENCY Antibodies	>3 publications with SERPINA6 and CORTICOSTEROID-BINDING GLOBULIN DEFICIENCY
Liver Diseases Antibodies	>2 publications with SERPINA6 and Liver Diseases
Obesity Antibodies	>2 publications with SERPINA6 and Obesity
Inflammation Antibodies	>2 publications with SERPINA6 and Inflammation
Adenocarcinoma Antibodies	>1 publications with SERPINA6 and Adenocarcinoma
Brain Diseases Antibodies	>1 publications with SERPINA6 and Brain Diseases

Organs/Tissues associated with SERPINA6 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>8 publications with SERPINA6 and Liver
Muscle Antibodies	>3 publications with SERPINA6 and Muscle
Uterus Antibodies	>2 publications with SERPINA6 and Uterus
Kidney Antibodies	>2 publications with SERPINA6 and Kidney