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Wingless-Type MMTV Integration Site Family, Member 2b (WNT2B) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS910522

MBS910522 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the wingless-type MMTV integration site family, member 2B (WNT2B) ELISA Kit target analytes in biological samples. The concentration… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
wingless-type MMTV integration site family, member 2B (WNT2B), ELISA Kit
Full Product Name
Human Protein Wnt-2b, WNT2B ELISA Kit
Product Gene Name
WNT2B elisa kit
Product Synonym Names
Human Protein Wnt-2b (WNT2B) ELISA kit; WNT13; XWNT2; XWNT2; Xenopus; homolog of; wingless-type MMTV integration site family; member 13; wingless-type MMTV integration site family; member 2B
Species Reactivity
Human
Samples
Serum, plasma, tissue homogenates, Cell lysates
Detection Range
62.5pg/ml-4000pg/ml
Sensitivity
15.6pg/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of Human WNT2B. No significant cross-reactivity or interference between Human WNT2B and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Molecular Weight
43,770 Da
OMIM
601968
3D Structure
ModBase 3D Structure for Q93097
Detection Wavelength
450 nm
Sample Volume
50-100ul
Protein Biological Process 1
Signaling Pathway
Protein Biological Process 3
Wnt signaling pathway
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of WNT2B elisa kit

Human WNT2B ELISA Kit – Cat# MBS910522

Other Notes

Small volumes of WNT2B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT2B. It may not necessarily be applicable to this product.

NCBI GI #
13518017
NCBI GeneID
7482
NCBI Accession #
NP_004176.2
UniProt Primary Accession #
Q93097
UniProt Secondary Accession #
O14903; Q5TEH9; Q5TEI2; Q9HDC1; Q9HDC2
UniProt Related Accession #
Q93097
GenBank Nucleotide #
NM_004185.4
NCBI Official Full Name
protein Wnt-2b isoform WNT-2B1
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 2B
NCBI Official Symbol
WNT2B
NCBI Official Synonym Symbols
WNT13
UniProt Protein Name
Protein Wnt-2b
UniProt Synonym Protein Names
Protein Wnt-13
Protein Family
Protein
UniProt Gene Name
WNT2B
UniProt Synonym Gene Names
WNT13
UniProt Entry Name
WNT2B_HUMAN
NCBI Protein Information
protein Wnt-2b; XWNT2, Xenopus, homolog of; wingless-type MMTV integration site family, member 13

NCBI Summary for WNT2B

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
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UniProt Comments for WNT2B

WNT2B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: lens development in camera-type eye; neuron differentiation; cell fate commitment; Wnt receptor signaling pathway; male gonad development; chondrocyte differentiation; Wnt receptor signaling pathway through beta-catenin; cellular response to starvation; forebrain regionalization
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Research Articles on WNT2B

1. secretion of WNT2B and WNT9B and stabilization of beta-catenin (CTNNB1) upon virus infection negatively regulate expression of representative inducible genes IFNB1, IFIT1 and TNF in a CTNNB1-dependent effector mechanism

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with WNT2B elisa kit

 Reference Product  PubMed Publications
 FZD5 elisa kit  >10 publications with WNT2B and FZD5
 FZD6 elisa kit  >9 publications with WNT2B and FZD6
 FZD4 elisa kit  >9 publications with WNT2B and FZD4
 SFRP1 elisa kit  >8 publications with WNT2B and SFRP1
 FZD10 elisa kit  >7 publications with WNT2B and FZD10
 FZD7 elisa kit  >7 publications with WNT2B and FZD7
 FZD2 elisa kit  >7 publications with WNT2B and FZD2
 FZD1 elisa kit  >6 publications with WNT2B and FZD1
 FZD9 elisa kit  >4 publications with WNT2B and FZD9
 FZD8 elisa kit  >4 publications with WNT2B and FZD8

Pathways associated with WNT2B elisa kit

 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram

Diseases associated with WNT2B elisa kit

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >8 publications with WNT2B and Breast Neoplasms
 Necrosis Antibodies  >4 publications with WNT2B and Necrosis
 Inflammation Antibodies  >4 publications with WNT2B and Inflammation
 Disease Models, Animal Antibodies  >2 publications with WNT2B and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >2 publications with WNT2B and Neoplasms, Experimental
 Neural Tube Defects Antibodies  >2 publications with WNT2B and Neural Tube Defects
 Neoplasm Metastasis Antibodies  >2 publications with WNT2B and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >2 publications with WNT2B and Ovarian Neoplasms
 Congenital Abnormalities Antibodies  >2 publications with WNT2B and Congenital Abnormalities
 Brain Diseases Antibodies  >1 publications with WNT2B and Brain Diseases

Organs/Tissues associated with WNT2B elisa kit

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >23 publications with WNT2B and Embryonic Tissue
 Eye Antibodies  >17 publications with WNT2B and Eye
 Brain Antibodies  >16 publications with WNT2B and Brain
 Lung Antibodies  >16 publications with WNT2B and Lung
 Kidney Antibodies  >8 publications with WNT2B and Kidney
 Testis Antibodies  >6 publications with WNT2B and Testis
 Skin Antibodies  >4 publications with WNT2B and Skin
 Prostate Antibodies  >4 publications with WNT2B and Prostate
 Placenta Antibodies  >4 publications with WNT2B and Placenta
 Ovary Antibodies  >2 publications with WNT2B and Ovary
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