Ficolin (Collagen/Fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2) ELISA Kit for Mouse

Name: Mouse FCN2 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS918223
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS918223

MBS918223 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2) ELISA Kit target analytes in biological samples. The… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) (FCN2), ELISA Kit

Full Product Name

Mouse Ficolin-2, FCN2 ELISA Kit

Product Gene Name

FCN2 elisa kit

Product Synonym Names

Mouse Ficolin-2 (FCN2) ELISA kit; RP11-263F14.2; EBP-37; FCNL; P35; ficolin-2; L-ficolin; collagen/fibrinogen domain-containing protein 2; ficolin 2; ficolin B; serum lectin p35; ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

Species Reactivity

Mouse

Specificity

This assay has high sensitivity and excellent specificity for detection of Mouse FCN2. No significant cross-reactivity or interference between Mouse FCN2 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

33,984 Da

3D Structure

ModBase 3D Structure for O70497

Detection Wavelength

450 nm

Sample Volume

50-100ul

Protein Biological Process 1

Complement

Protein Biological Process 3

Complement activation lectin pathway

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FCN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FCN2. It may not necessarily be applicable to this product.

NCBI GI #

77404440

NCBI GeneID

14134

NCBI Accession #

NP_034320.1

UniProt Primary Accession #

O70497

UniProt Secondary Accession #

Q3KNL6

UniProt Related Accession #

O70497

GenBank Nucleotide #

NM_010190.1

NCBI Official Full Name

ficolin-2

NCBI Official Synonym Full Names

ficolin B

NCBI Official Symbol

Fcnb

NCBI Official Synonym Symbols

Fcn2

UniProt Protein Name

Ficolin-2

UniProt Synonym Protein Names

Collagen/fibrinogen domain-containing protein 2; Ficolin-B; Ficolin-beta; L-ficolin

Protein Family

Ficolin

UniProt Gene Name

Fcn2

UniProt Synonym Gene Names

Fcnb

UniProt Entry Name

FCN2_MOUSE

NCBI Protein Information

ficolin-2; L-ficolin; ficolin-B; ficolin-beta; collagen/fibrinogen domain-containing protein 2

UniProt Comments for FCN2

FCN2: May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. Belongs to the ficolin lectin family. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: extrinsic to external side of plasma membrane; collagen; extracellular region

Molecular Function: G-protein-coupled receptor binding; carbohydrate binding; sialic acid binding; pattern recognition receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of virion penetration into host cell; immune system process; cell surface pattern recognition receptor signaling pathway; innate immune response; complement activation, lectin pathway; recognition of apoptotic cell

Research Articles on FCN2

1. Ficolin-2 defends against virulent Mycobacteria tuberculosis infection in vivo, and its insufficiency is associated with infection in humans.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with FCN2 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with FCN2 and Liver