Melanoma Inhibitory Activity Protein 1 (MIA1) ELISA Kit for Human

Name: Human MIA1 ELISA Kit; Melanoma Inhibitory Activity Protein 1; MyBioSource
Brand: MyBioSource
SKU: MBS092307
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS092307

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of MIA1 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Melanoma Inhibitory Activity Protein 1 (MIA1), ELISA Kit

Full Product Name

Human Melanoma Inhibitory Activity Protein 1 ELISA Kit

Product Gene Name

MIA1 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Undiluted original Human serum, plasma or tissue homogenates samples

Detection Range

1.56ng/ml-50ng/ml

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

213,702 Da

OMIM

613455

3D Structure

ModBase 3D Structure for Q5JRA6

Other Notes

Small volumes of MIA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIA1 purchase

MBS092307 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Melanoma Inhibitory Activity Protein 1 (MIA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MIA1. The ELISA analytical biochemical technique of the MBS092307 kit is based on MIA1 antibody-MIA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MIA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MIA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MIA1. It may not necessarily be applicable to this product.

NCBI GI #

122891870

NCBI GeneID

375056

NCBI Accession #

NP_940953.2

UniProt Primary Accession #

Q5JRA6

UniProt Secondary Accession #

Q14083; Q3S4X3; Q5JRA5; Q5JRB0; Q5JRB1; Q5JRB2; Q6UVY8; A8K2S0; A8MT05; A8MT13; B7Z430

UniProt Related Accession #

Q5JRA6

GenBank Nucleotide #

NM_198551.3

NCBI Official Full Name

melanoma inhibitory activity protein 3 isoform 1

NCBI Official Synonym Full Names

melanoma inhibitory activity family, member 3

NCBI Official Symbol

MIA3

NCBI Official Synonym Symbols

ARNT; D320; TANGO; TANGO1; UNQ6077

UniProt Protein Name

Melanoma inhibitory activity protein 3

UniProt Synonym Protein Names

C219-reactive peptide; D320; Transport and Golgi organization protein 1

UniProt Gene Name

MIA3

UniProt Synonym Gene Names

KIAA0268; TANGO; TANGO1

UniProt Entry Name

MIA3_HUMAN

NCBI Protein Information

melanoma inhibitory activity protein 3; C219-reactive peptide; transport and Golgi organization protein 1

UniProt Comments for MIA1

MIA3: Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. Belongs to the MIA/OTOR family. Tango1 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Endoplasmic reticulum; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; integral to membrane

Molecular Function: protein binding

Biological Process: protein transport; exocytosis; collagen fibril organization; wound healing; positive regulation of leukocyte migration; chondrocyte development; negative regulation of cell adhesion; positive regulation of bone mineralization; negative regulation of cell migration

Research Articles on MIA1

1. We conclude that SNP rs17465637 in MIA3 is indeed a genetic risk factor for CAD across different ethnic populations including Han Chinese.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with MIA1 elisa kit

Disease Name	Pubmed Publications
Coronary Artery Disease Antibodies	>4 publications with MIA1 and Coronary Artery Disease
Myocardial Infarction Antibodies	>4 publications with MIA1 and Myocardial Infarction
Atherosclerosis Antibodies	>3 publications with MIA1 and Atherosclerosis
Hypertension Antibodies	>1 publications with MIA1 and Hypertension

Organs/Tissues associated with MIA1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with MIA1 and Blood
Heart Antibodies	>2 publications with MIA1 and Heart
Vascular Antibodies	>1 publications with MIA1 and Vascular
Mouth Antibodies	>1 publications with MIA1 and Mouth
Bone Antibodies	>1 publications with MIA1 and Bone
Liver Antibodies	>1 publications with MIA1 and Liver