Gamma-Glutamyltransferase 1 (GGT1) ELISA Kit for Rat

Name: Rat GGT1 ELISA Kit; Gamma-Glutamyltransferase 1; MyBioSource
Brand: MyBioSource
SKU: MBS923419
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS923419

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GFAP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GFAP present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

gamma-glutamyltransferase 1 (GGT1), ELISA Kit

Full Product Name

Rat Gamma-glutamyltranspeptidase 1, GGT1 ELISA Kit

Product Gene Name

GGT1 elisa kit

Product Synonym Names

Rat Gamma-glutamyltranspeptidase 1 (GGT1) ELISA kit; CD224; D22S672; D22S732; GGT; GTG; MGC96892; MGC96904; MGC96963; OTTHUMP00000028921; OTTHUMP00000159078; gamma-glutamyl transpeptidase; glutamyl transpeptidase; gamma-glutamyltransferase 1

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Serum, Plasma, Tissue Homogenates

Detection Range

0.625 ng/ml-40 ng/ml

Sensitivity

0.156 ng/ml.

Specificity

This assay has high sensitivity and excellent specificity for detection of human GFAP. No significant cross-reactivity or interference between human GFAP and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess

Molecular Weight

61,610 Da

3D Structure

ModBase 3D Structure for P07314

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GGT1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GGT1 purchase

MBS923419 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the gamma-glutamyltransferase 1 (GGT1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GGT1. The ELISA analytical biochemical technique of the MBS923419 kit is based on GGT1 antibody-GGT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GGT1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GGT1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GGT1. It may not necessarily be applicable to this product.

NCBI GI #

145280505

NCBI GeneID

116568

NCBI Accession #

NP_446292.2

UniProt Primary Accession #

P07314

UniProt Secondary Accession #

Q63217; Q63218; Q6AZ32

UniProt Related Accession #

P07314

GenBank Nucleotide #

NM_053840.2

NCBI Official Full Name

gamma-glutamyltranspeptidase 1

NCBI Official Synonym Full Names

gamma-glutamyltransferase 1

NCBI Official Symbol

Ggt1

NCBI Official Synonym Symbols

Ggt; Ggtp; GGLUT

UniProt Protein Name

Gamma-glutamyltranspeptidase 1

UniProt Synonym Protein Names

Gamma-glutamyltransferase 1; Glutathione hydrolase 1 (EC:3.4.19.13); Leukotriene-C4 hydrolase (EC:3.4.19.14); CD_antigen: CD224Cleaved into the following 2 chains:Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain

Protein Family

Gamma-glutamyltranspeptidase

UniProt Gene Name

Ggt1

UniProt Synonym Gene Names

Ggt; GGT 1

UniProt Entry Name

GGT1_RAT

NCBI Protein Information

gamma-glutamyltranspeptidase 1; GGT 1; glutathione hydrolase 1; leukotriene-C4 hydrolase; gamma glutamyl-transferase 1; gamma-glutamyl transpeptidase

NCBI Summary for GGT1

required in the glutathione metabolism [RGD, Feb 2006]

UniProt Comments for GGT1

GGT1: Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive. Defects in GGT1 are a cause of glutathionuria (GLUTH); also known as gamma-glutamyltranspeptidase deficiency. It is an autosomal recessive disease. Belongs to the gamma-glutamyltransferase family. 3 isoforms of the human protein are produced by alternative promoter.

Protein type: Membrane protein, integral; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; Transferase; EC 3.4.19.14; EC 3.4.19.13; EC 2.3.2.2; Other Amino Acids Metabolism - taurine and hypotaurine; Other Amino Acids Metabolism - selenoamino acid; Other Amino Acids Metabolism - glutathione

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane

Molecular Function: gamma-glutamyltransferase activity

Biological Process: peptide modification; glutamate metabolic process; regulation of immune system process; cysteine biosynthetic process; response to lipopolysaccharide; proteolysis; response to estradiol stimulus; leukotriene biosynthetic process; regulation of inflammatory response; glutathione catabolic process; glutathione biosynthetic process; spermatogenesis; zymogen activation; aging

Research Articles on GGT1

1. These data demonstrate the important role of endothelial GGT activity in mediating the vasorelaxant effect of S-nitrosoglutathione in rat aorta .

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GGT1 elisa kit

Products by Pathway	Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Cyanoamino Acid Metabolism Pathway antibodies	Cyanoamino Acid Metabolism Pathway Diagram
Cyanoamino Acid Metabolism Pathway antibodies	Cyanoamino Acid Metabolism Pathway Diagram
Eicosanoid Synthesis Pathway antibodies	Eicosanoid Synthesis Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Taurine And Hypotaurine Metabolism Pathway antibodies	Taurine And Hypotaurine Metabolism Pathway Diagram
Taurine And Hypotaurine Metabolism Pathway antibodies	Taurine And Hypotaurine Metabolism Pathway Diagram

Diseases associated with GGT1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with GGT1 and Neoplasms
Liver Diseases Antibodies	>5 publications with GGT1 and Liver Diseases
Carcinoma Antibodies	>3 publications with GGT1 and Carcinoma
Cardiovascular Diseases Antibodies	>3 publications with GGT1 and Cardiovascular Diseases
Skin Diseases Antibodies	>2 publications with GGT1 and Skin Diseases
Lung Diseases Antibodies	>2 publications with GGT1 and Lung Diseases
Heart Diseases Antibodies	>2 publications with GGT1 and Heart Diseases
Abnormalities, Drug-Induced Antibodies	>1 publications with GGT1 and Abnormalities, Drug-Induced
Breast Neoplasms Antibodies	>1 publications with GGT1 and Breast Neoplasms
Hypertension Antibodies	>1 publications with GGT1 and Hypertension

Organs/Tissues associated with GGT1 elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>5 publications with GGT1 and Lung
Heart Antibodies	>2 publications with GGT1 and Heart
Uncharacterized Tissue Antibodies	>1 publications with GGT1 and Uncharacterized Tissue