Interferon, Alpha 21 (IFNA21) ELISA Kit for Human

Name: Human IFNA21 ELISA Kit; Interferon, Alpha 21; MyBioSource
Brand: MyBioSource
SKU: MBS926018
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS926018

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IFNA21 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IFNA21 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

interferon, alpha 21 (IFNA21), ELISA Kit

Full Product Name

Human Interferon alpha-21, IFNA21 ELISA Kit

Product Gene Name

IFNA21 elisa kit

Product Synonym Names

Human Interferon alpha-21 (IFNA21) ELISA kit; MGC126687; MGC126689; leukocyte interferon protein; interferon; alpha 21

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates

Detection Range

15.6 pg/ml-1000 pg/ml

Sensitivity

3.9 pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Human IFNA21. No significant cross-reactivity or interference between Human IFNA21 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

21,741 Da

OMIM

147584

3D Structure

ModBase 3D Structure for P01568

Detection Wavelength

450 nm

Sample Volume

50-100ul

Protein Biological Process 1

Immunity

Protein Biological Process 3

Antiviral defense

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IFNA21 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFNA21 purchase

MBS926018 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interferon, alpha 21 (IFNA21) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IFNA21. The ELISA analytical biochemical technique of the MBS926018 kit is based on IFNA21 antibody-IFNA21 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IFNA21 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IFNA21. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IFNA21. It may not necessarily be applicable to this product.

NCBI GI #

169791013

NCBI GeneID

3452

NCBI Accession #

NP_002166.2

UniProt Primary Accession #

P01568

UniProt Secondary Accession #

Q14608; Q5VWD1; Q7M4Q4

UniProt Related Accession #

P01568

GenBank Nucleotide #

NM_002175.2

NCBI Official Full Name

interferon alpha-21

NCBI Official Synonym Full Names

interferon, alpha 21

NCBI Official Symbol

IFNA21

NCBI Official Synonym Symbols

LeIF F; leIF-F; IFN-alphaI

UniProt Protein Name

Interferon alpha-21

UniProt Synonym Protein Names

Interferon alpha-F; LeIF F

Protein Family

Interferon

UniProt Gene Name

IFNA21

UniProt Synonym Gene Names

IFN-alpha-21; LeIF F

UniProt Entry Name

IFN21_HUMAN

NCBI Protein Information

interferon alpha-21; IFN-alpha-21; interferon alpha-F; leukocyte interferon protein

NCBI Summary for IFNA21

This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]

UniProt Comments for IFNA21

IFNA21: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein

Research Articles on IFNA21

1. Structural AA changes in the C-helix interacting with IFNAlphaR1 may change the signaling dynamics leading to elevated APOBEC3 & lower IDO by an engineered mutant derived from the amino-terminal region of IFNalpha21b and the COOH-terminus from IFNalpha2c.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IFNA21 elisa kit

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Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
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Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Hepatitis C Pathway antibodies	Hepatitis C Pathway Diagram

Diseases associated with IFNA21 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1 publications with IFNA21 and Nervous System Diseases
Mental Disorders Antibodies	>1 publications with IFNA21 and Mental Disorders
Parkinson Disease Antibodies	>1 publications with IFNA21 and Parkinson Disease
Dementia Antibodies	>1 publications with IFNA21 and Dementia
Genetic Predisposition to Disease Antibodies	>1 publications with IFNA21 and Genetic Predisposition to Disease