Neuromedin U (NMU) ELISA Kit for Human

Name: Human NMU ELISA Kit; Neuromedin U; MyBioSource
Brand: MyBioSource
SKU: MBS929593
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS929593

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for NMU has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any NMU present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

neuromedin U (NMU), ELISA Kit

Full Product Name

Human neuromedin U, NMU ELISA Kit

Product Gene Name

NMU elisa kit

Product Synonym Names

Human neuromedin U (NMU) ELISA kit; neuromedin U

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, cerebrospinal fluid (CSF) and tissue homogenates

Detection Range

0.312 ng/ml-20 ng/ml

Sensitivity

0.078 ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Human NMU. No significant cross-reactivity or interference between Human NMU and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

19,741 Da

OMIM

605103

3D Structure

ModBase 3D Structure for P48645

Detection Wavelength

450 nm

Sample Volume

50-100ul

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NMU elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NMU purchase

MBS929593 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the neuromedin U (NMU) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NMU. The ELISA analytical biochemical technique of the MBS929593 kit is based on NMU antibody-NMU antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NMU antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NMU. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for NMU. It may not necessarily be applicable to this product.

NCBI GI #

5729947

NCBI GeneID

10874

NCBI Accession #

NP_006672.1

UniProt Primary Accession #

P48645

UniProt Related Accession #

P48645

GenBank Nucleotide #

NM_006681.3

NCBI Official Full Name

neuromedin-U isoform 1 preproprotein

NCBI Official Synonym Full Names

neuromedin U

NCBI Official Symbol

NMU

UniProt Protein Name

Neuromedin-U

Protein Family

Neuromedin

UniProt Gene Name

NMU

UniProt Synonym Gene Names

NmU-25

UniProt Entry Name

NMU_HUMAN

NCBI Protein Information

neuromedin-U; prepro-NMU

NCBI Summary for NMU

This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]

UniProt Comments for NMU

NMU: Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. Belongs to the NmU family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q12

Cellular Component: extracellular region; terminal button

Molecular Function: neuromedin U receptor binding; receptor binding

Biological Process: regulation of smooth muscle contraction; gastric acid secretion; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; eating behavior; photoperiodism; digestion; positive regulation of hormone secretion; positive regulation of smooth muscle contraction; sensory perception of pain; signal transduction; positive regulation of synaptic transmission

Research Articles on NMU

1. a role for NMU gene through interaction with ADRB2 gene in bone strength regulation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NMU elisa kit

Reference Product	PubMed Publications
NMUR1 elisa kit	>22 publications with NMU and NMUR1
NMUR2 elisa kit	>19 publications with NMU and NMUR2

Pathways associated with NMU elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with NMU elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>422 publications with NMU and Neoplasms
Neoplasms, Experimental Antibodies	>288 publications with NMU and Neoplasms, Experimental
Mammary Neoplasms, Experimental Antibodies	>219 publications with NMU and Mammary Neoplasms, Experimental
Drug Toxicity Antibodies	>100 publications with NMU and Drug Toxicity
Breast Neoplasms Antibodies	>87 publications with NMU and Breast Neoplasms
Nervous System Diseases Antibodies	>74 publications with NMU and Nervous System Diseases
Liver Neoplasms Antibodies	>47 publications with NMU and Liver Neoplasms
Cardiovascular Diseases Antibodies	>43 publications with NMU and Cardiovascular Diseases
Brain Diseases Antibodies	>41 publications with NMU and Brain Diseases
Gastrointestinal Diseases Antibodies	>32 publications with NMU and Gastrointestinal Diseases

Organs/Tissues associated with NMU elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>131 publications with NMU and Brain
Intestine Antibodies	>36 publications with NMU and Intestine
Stomach Antibodies	>23 publications with NMU and Stomach
Pancreas Antibodies	>21 publications with NMU and Pancreas
Connective Tissue Antibodies	>16 publications with NMU and Connective Tissue
Bone Marrow Antibodies	>15 publications with NMU and Bone Marrow
Ovary Antibodies	>13 publications with NMU and Ovary
Testis Antibodies	>9 publications with NMU and Testis
Embryonic Tissue Antibodies	>8 publications with NMU and Embryonic Tissue
Lymph Antibodies	>6 publications with NMU and Lymph