Integrin, Alpha 1 (ITGA1) ELISA Kit for Human

Name: Human ITGA1 ELISA Kit; Integrin, Alpha 1; MyBioSource
Brand: MyBioSource
SKU: MBS930698
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS930698

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ITGA1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ITGA1 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

integrin, alpha 1 (ITGA1), ELISA Kit

Full Product Name

Human Integrin alpha-1, ITGA1 ELISA Kit

Product Gene Name

ITGA1 elisa kit

Product Synonym Names

Human Integrin alpha-1 (ITGA1) ELISA kit; CD49a; VLA1; laminin and collagen receptor; very late activation protein 1; integrin; alpha 1

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, tissue homogenates

Detection Range

0.312 ng/ml-20 ng/ml

Sensitivity

<0.078 ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of human ITGA1. No significant cross-reactivity or interference between human ITGA1 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

130,848 Da

OMIM

192968

3D Structure

ModBase 3D Structure for P56199

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ITGA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ITGA1 purchase

MBS930698 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the integrin, alpha 1 (ITGA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITGA1. The ELISA analytical biochemical technique of the MBS930698 kit is based on ITGA1 antibody-ITGA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITGA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITGA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ITGA1. It may not necessarily be applicable to this product.

NCBI GI #

31657142

NCBI GeneID

3672

NCBI Accession #

NP_852478.1

UniProt Primary Accession #

P56199

UniProt Secondary Accession #

B2RNU0

UniProt Related Accession #

P56199

GenBank Nucleotide #

NM_181501.1

NCBI Official Full Name

integrin alpha-1

NCBI Official Synonym Full Names

integrin, alpha 1

NCBI Official Symbol

ITGA1

NCBI Official Synonym Symbols

VLA1; CD49a

UniProt Protein Name

Integrin alpha-1

UniProt Synonym Protein Names

CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1; CD_antigen: CD49a

Protein Family

Integrin

UniProt Gene Name

ITGA1

UniProt Entry Name

ITA1_HUMAN

NCBI Protein Information

integrin alpha-1; VLA-1; laminin and collagen receptor; very late activation protein 1; CD49 antigen-like family member A

NCBI Summary for ITGA1

This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

UniProt Comments for ITGA1

ITGA1: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Belongs to the integrin alpha chain family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: neuron projection; focal adhesion; cell surface; membrane; acrosome; plasma membrane; perikaryon; integrin complex; lipid raft; external side of plasma membrane

Molecular Function: collagen binding; protein binding; metal ion binding; protein phosphatase binding; receptor binding

Biological Process: negative regulation of epidermal growth factor receptor signaling pathway; positive regulation of phosphoprotein phosphatase activity; integrin-mediated signaling pathway; axon guidance; neutrophil chemotaxis; extracellular matrix organization and biogenesis; activation of MAPK activity; cell-matrix adhesion; vasodilation; negative regulation of cell proliferation; muscle contraction; cellular extravasation; positive regulation of neuron apoptosis; blood coagulation

Research Articles on ITGA1

1. 17-beta-estradiol modulates connexins and integrins as well as ER-beta expression induced by high frequency electromagnetic fields.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ITGA1 elisa kit

Reference Product	PubMed Publications
ITGB5 elisa kit	>1 publications with ITGA1 and ITGB5
LAMA1 elisa kit	>1 publications with ITGA1 and LAMA1
ITGB1 elisa kit	>1 publications with ITGA1 and ITGB1

Pathways associated with ITGA1 elisa kit

Products by Pathway	Pathway Diagram
Arf6 Trafficking Events Pathway antibodies	Arf6 Trafficking Events Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
CHL1 Interactions Pathway antibodies	CHL1 Interactions Pathway Diagram
CXCR4-mediated Signaling Events Pathway antibodies	CXCR4-mediated Signaling Events Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram
Dilated Cardiomyopathy Pathway antibodies	Dilated Cardiomyopathy Pathway Diagram

Diseases associated with ITGA1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>4 publications with ITGA1 and Inflammation
Fibrosis Antibodies	>2 publications with ITGA1 and Fibrosis
Necrosis Antibodies	>2 publications with ITGA1 and Necrosis
Nervous System Malformations Antibodies	>1 publications with ITGA1 and Nervous System Malformations
Breast Neoplasms Antibodies	>1 publications with ITGA1 and Breast Neoplasms
Prostatic Diseases Antibodies	>1 publications with ITGA1 and Prostatic Diseases
Cardiovascular Diseases Antibodies	>1 publications with ITGA1 and Cardiovascular Diseases
Lung Neoplasms Antibodies	>1 publications with ITGA1 and Lung Neoplasms
Ovarian Neoplasms Antibodies	>1 publications with ITGA1 and Ovarian Neoplasms

Organs/Tissues associated with ITGA1 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>6 publications with ITGA1 and Bone
Blood Antibodies	>4 publications with ITGA1 and Blood
Muscle Antibodies	>3 publications with ITGA1 and Muscle
Brain Antibodies	>3 publications with ITGA1 and Brain
Vascular Antibodies	>2 publications with ITGA1 and Vascular
Liver Antibodies	>2 publications with ITGA1 and Liver
Placenta Antibodies	>2 publications with ITGA1 and Placenta
Embryonic Tissue Antibodies	>1 publications with ITGA1 and Embryonic Tissue
Heart Antibodies	>1 publications with ITGA1 and Heart
Adipose Tissue Antibodies	>1 publications with ITGA1 and Adipose Tissue