Ras Homolog Gene Family, Member A (RHOA) ELISA Kit for Cat

Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

RHOD: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. Belongs to the small GTPase superfamily. Rho family.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric, Rho; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 11q14.3

Cellular Component: early endosome; plasma membrane; cytosol

Molecular Function: GTPase activity; GTP binding; protein kinase binding

Biological Process: focal adhesion formation; lamellipodium biogenesis; actin filament bundle formation; regulation of small GTPase mediated signal transduction; positive regulation of cell adhesion; metabolic process; small GTPase mediated signal transduction; regulation of focal adhesion formation; Rho protein signal transduction; positive regulation of cell migration; protein targeting