Platelet Derived Growth Factor Cc (PDGF-CC) ELISA Kit for Rat

Name: Rat PDGF-CC ELISA Kit; Platelet Derived Growth Factor Cc; MyBioSource
Brand: MyBioSource
SKU: MBS933756
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS933756

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PDGF-CC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PDGF-CC present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

platelet derived growth factor CC (PDGF-CC), ELISA Kit

Full Product Name

Rat Platelet-derived growth factor CC, PDGF-CC ELISA Kit

Product Gene Name

PDGF-CC elisa kit

Product Synonym Names

Rat Platelet-derived growth factor CC (PDGF-CC) ELISA kit; platelet derived growth factor CC

Species Reactivity

Rat

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates

Detection Range

15.6 pg/ml -1000 pg/ml.

Sensitivity

The minimum detectable dose of rat PDGF-CC is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

Specificity

This assay has high sensitivity and excellent specificity for detection of rat PDGF-CC. No significant cross-reactivity or interference between rat PDGF-CC and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

38,734 Da

3D Structure

ModBase 3D Structure for Q9EQX6

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PDGF-CC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDGF-CC purchase

MBS933756 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the platelet derived growth factor CC (PDGF-CC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDGF-CC. The ELISA analytical biochemical technique of the MBS933756 kit is based on PDGF-CC antibody-PDGF-CC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDGF-CC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDGF-CC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PDGF-CC. It may not necessarily be applicable to this product.

NCBI GI #

13786136

NCBI GeneID

79429

NCBI Accession #

NP_112607.1

UniProt Primary Accession #

Q9EQX6

UniProt Secondary Accession #

Q8K429

UniProt Related Accession #

Q9EQX6

GenBank Nucleotide #

NM_031317.1

NCBI Official Full Name

platelet-derived growth factor C

NCBI Official Synonym Full Names

platelet derived growth factor C

NCBI Official Symbol

Pdgfc

NCBI Official Synonym Symbols

SCDGF

UniProt Protein Name

Platelet-derived growth factor C

UniProt Synonym Protein Names

Fallotein; Spinal cord-derived growth factor; rScdfg; VEGF-ECleaved into the following 2 chains:Platelet-derived growth factor C, latent form; PDGFC latent form; Platelet-derived growth factor C, receptor-binding form; PDGFC receptor-binding form

UniProt Gene Name

Pdgfc

UniProt Synonym Gene Names

Scdgf; PDGF-C; rScdfg; PDGFC latent form; PDGFC receptor-binding form

UniProt Entry Name

PDGFC_RAT

NCBI Protein Information

platelet-derived growth factor C; PDGF-C; VEGF-E; rScdfg; fallotein; spinal cord-derived growth factor; platelet-derived growth factor, C polypeptide

NCBI Summary for PDGF-CC

expressed in the embryonic spinal cord floor plate and ventricular zone, adult expression is localized to motoneurons in several regions of the brain [RGD, Feb 2006]

UniProt Comments for PDGF-CC

Function: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function

Research Articles on PDGF-CC

1. After experimental liver fibrosis, induced by bile-duct occlusion, miR-29 expression was shown to be reduced, but IGF-I and PDGF-C expression was upregulated, correlating inversely to the miR-29 pattern.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PDGF-CC elisa kit

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Diseases associated with PDGF-CC elisa kit

Disease Name	Pubmed Publications
Cleft Palate Antibodies	>7 publications with PDGF-CC and Cleft Palate
Congenital Abnormalities Antibodies	>5 publications with PDGF-CC and Congenital Abnormalities
Adenocarcinoma Antibodies	>4 publications with PDGF-CC and Adenocarcinoma
Cleft Lip Antibodies	>4 publications with PDGF-CC and Cleft Lip
Lung Neoplasms Antibodies	>4 publications with PDGF-CC and Lung Neoplasms
Liver Diseases Antibodies	>3 publications with PDGF-CC and Liver Diseases
Liver Neoplasms Antibodies	>3 publications with PDGF-CC and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>3 publications with PDGF-CC and Carcinoma, Hepatocellular
Disease Models, Animal Antibodies	>3 publications with PDGF-CC and Disease Models, Animal
Neoplasms, Experimental Antibodies	>3 publications with PDGF-CC and Neoplasms, Experimental

Organs/Tissues associated with PDGF-CC elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>2 publications with PDGF-CC and Liver