Dog MDC/CCL22 ELISA Kit – Cat# MBS934113

Macrophage-Derived Chemokine (MDC/CCL22) (MDC/CCL22) ELISA Kit for Dog

Name: Dog MDC/CCL22 ELISA Kit; Macrophage-Derived Chemokine (MDC/CCL22); MyBioSource
Brand: MyBioSource
SKU: MBS934113
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS934113

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for MDC/CCL22 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MDC/CCL22 present is bound by… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Macrophage-Derived Chemokine (MDC/CCL22), ELISA Kit

Full Product Name

Canine Macrophage-Derived Chemokine, MDC/CCL22 ELISA Kit

Product Gene Name

MDC/CCL22 elisa kit

Product Synonym Names

Canine Macrophage-Derived Chemokine (MDC/CCL22) ELISA Kit; A-152E5.1; ABCD-1; DC/B-CK; MDC; MGC34554; SCYA22; STCP-1; CC chemokine STCP-1; macrophage-derived chemokine; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys); member 22; sti; Macrophage-Derived Chemokine (MDC/CCL22)

Species Reactivity

Dog

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, tissue homogenates

Detection Range

0.156 ng/ml-10 ng/ml

Sensitivity

< 0.039 ng/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of canine MDC/CCL22. No significant cross-reactivity or interference between canine MDC/CCL22 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%.Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

83,418 Da

OMIM

155120

3D Structure

ModBase 3D Structure for O75078

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MDC/CCL22 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MDC/CCL22 purchase

MBS934113 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Macrophage-Derived Chemokine (MDC/CCL22) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MDC/CCL22. The ELISA analytical biochemical technique of the MBS934113 kit is based on MDC/CCL22 antibody-MDC/CCL22 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MDC/CCL22 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MDC/CCL22. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MDC/CCL22. It may not necessarily be applicable to this product.

NCBI GI #

4585710

NCBI GeneID

4185

NCBI Accession #

NP_002381.2

UniProt Primary Accession #

O75078

UniProt Secondary Accession #

Q14808; Q14809; Q14810

UniProt Related Accession #

O75078; AAB29191

GenBank Nucleotide #

NM_002390.4

NCBI Official Full Name

disintegrin and metalloproteinase domain-containing protein 11 preproprotein

NCBI Official Synonym Full Names

ADAM metallopeptidase domain 11

NCBI Official Symbol

ADAM11

NCBI Official Synonym Symbols

MDC

UniProt Protein Name

Disintegrin and metalloproteinase domain-containing protein 11

UniProt Synonym Protein Names

Metalloproteinase-like, disintegrin-like, and cysteine-rich protein; MDC

UniProt Gene Name

ADAM11

UniProt Synonym Gene Names

MDC; ADAM 11; MDC

UniProt Entry Name

ADA11_HUMAN

NCBI Protein Information

disintegrin and metalloproteinase domain-containing protein 11; ADAM 11

NCBI Summary for MDC/CCL22

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008]

UniProt Comments for MDC/CCL22

ADAM11: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: extracellular matrix; plasma membrane; integral to membrane

Molecular Function: integrin binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity

Biological Process: integrin-mediated signaling pathway; proteolysis

Research Articles on MDC/CCL22

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with MDC/CCL22 elisa kit

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>3 publications with MDC/CCL22 and Lung Diseases
Brain Diseases Antibodies	>2 publications with MDC/CCL22 and Brain Diseases
Epilepsy Antibodies	>1 publications with MDC/CCL22 and Epilepsy
Carcinoma Antibodies	>1 publications with MDC/CCL22 and Carcinoma
Lymphatic Diseases Antibodies	>1 publications with MDC/CCL22 and Lymphatic Diseases
Seizures Antibodies	>1 publications with MDC/CCL22 and Seizures
Urticaria Antibodies	>1 publications with MDC/CCL22 and Urticaria
Necrosis Antibodies	>1 publications with MDC/CCL22 and Necrosis

Organs/Tissues associated with MDC/CCL22 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>9 publications with MDC/CCL22 and Brain
Skin Antibodies	>1 publications with MDC/CCL22 and Skin
Heart Antibodies	>1 publications with MDC/CCL22 and Heart