Growth Arrest-Specific 6 (GAS6) ELISA Kit for Mouse

Name: Mouse GAS6 ELISA Kit; Growth Arrest-Specific 6; MyBioSource
Brand: MyBioSource
SKU: MBS939560
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS939560

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for gas-6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any gas-6 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

growth arrest-specific 6 (GAS6), ELISA Kit

Full Product Name

Mouse growth arrest-specific gene-6, gas-6 ELISA Kit

Product Gene Name

GAS6 elisa kit

Product Synonym Names

Mouse growth arrest-specific gene-6 (gas-6) ELISA Kit; AXLLG; AXSF; DKFZp666G247; FLJ34709; AXL receptor tyrosine kinase ligand; AXL stimulatory factor; Mouse growth arrest-specific gene-6 (gas-6)

Species Reactivity

Mouse

Assay Type

Sandwich

Detection Range

31.25pg/ml-2000pg/ml

Sensitivity

17.086 pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Mouse GAS6. No significant cross-reactivity or interference between Mouse GAS6 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

74,610 Da

3D Structure

ModBase 3D Structure for Q61592

Detection Wavelength

450 nm

Sample Volume

50-100ul

Protein Biological Process 1

Cardiovascular

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GAS6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAS6 purchase

MBS939560 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the growth arrest-specific 6 (GAS6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GAS6. The ELISA analytical biochemical technique of the MBS939560 kit is based on GAS6 antibody-GAS6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GAS6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GAS6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GAS6. It may not necessarily be applicable to this product.

NCBI GI #

145301603

NCBI GeneID

14456

NCBI Accession #

NP_062394.2

UniProt Primary Accession #

Q61592

UniProt Secondary Accession #

Q99K57

UniProt Related Accession #

Q61592

GenBank Nucleotide #

NM_019521.2

NCBI Official Full Name

growth arrest-specific protein 6

NCBI Official Synonym Full Names

growth arrest specific 6

NCBI Official Symbol

Gas6

NCBI Official Synonym Symbols

Gas-6

UniProt Protein Name

Growth arrest-specific protein 6

UniProt Synonym Protein Names

AXL receptor tyrosine kinase ligand

Protein Family

Growth arrest-specific protein

UniProt Gene Name

Gas6

UniProt Synonym Gene Names

GAS-6

UniProt Entry Name

GAS6_MOUSE

NCBI Protein Information

growth arrest-specific protein 6; GAS 6; AXL receptor tyrosine kinase ligand

UniProt Comments for GAS6

Function: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.1 PublicationManual assertion based on experiment in:Ref.3

Research Articles on GAS6

1. The expression of TAM receptor tyrosine kinases and their ligand Gas6 is markedly downregulated in psoriatic epidermis. These data are in concordance with earlier study, demonstrating that TAM-deficient mice develop systemic autoimmunity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GAS6 elisa kit

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Gamma-carboxylation Of Protein Precursors Pathway antibodies	Gamma-carboxylation Of Protein Precursors Pathway Diagram
Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway antibodies	Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies	PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway antibodies	Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway Diagram

Diseases associated with GAS6 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>53 publications with GAS6 and Neoplasms
Inflammation Antibodies	>43 publications with GAS6 and Inflammation
Vascular Diseases Antibodies	>42 publications with GAS6 and Vascular Diseases
Cardiovascular Diseases Antibodies	>39 publications with GAS6 and Cardiovascular Diseases
Necrosis Antibodies	>27 publications with GAS6 and Necrosis
Thrombosis Antibodies	>25 publications with GAS6 and Thrombosis
Disease Models, Animal Antibodies	>23 publications with GAS6 and Disease Models, Animal
Carcinoma Antibodies	>22 publications with GAS6 and Carcinoma
Kidney Diseases Antibodies	>21 publications with GAS6 and Kidney Diseases
Nervous System Diseases Antibodies	>19 publications with GAS6 and Nervous System Diseases

Organs/Tissues associated with GAS6 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>41 publications with GAS6 and Muscle
Bone Antibodies	>32 publications with GAS6 and Bone
Kidney Antibodies	>28 publications with GAS6 and Kidney
Brain Antibodies	>26 publications with GAS6 and Brain
Liver Antibodies	>20 publications with GAS6 and Liver
Bone Marrow Antibodies	>17 publications with GAS6 and Bone Marrow
Embryonic Tissue Antibodies	>14 publications with GAS6 and Embryonic Tissue
Eye Antibodies	>13 publications with GAS6 and Eye
Heart Antibodies	>8 publications with GAS6 and Heart
Lung Antibodies	>7 publications with GAS6 and Lung