Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2) ELISA Kit for Human

Name: Human ENOX2 ELISA Kit; Ecto-NOX Disulfide-Thiol Exchanger 2; MyBioSource
Brand: MyBioSource
SKU: MBS943476
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS943476

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ENOX2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ENOX2 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

ecto-NOX disulfide-thiol exchanger 2 (ENOX2), ELISA Kit

Full Product Name

Human Ecto-NOX disulfide-thiol exchanger 2, ENOX2 ELISA Kit

Product Gene Name

ENOX2 elisa kit

Product Synonym Names

Human Ecto-NOX disulfide-thiol exchanger 2 (ENOX2) ELISA kit; RP5-875H3.1; APK1; COVA1; tNOX; APK1 antigen; OTTHUMP00000024021; OTTHUMP00000024022; cytosolic ovarian carcinoma antigen 1; ecto-NOX disulfide-thiol exchanger 2

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates

Detection Range

31.25 pg/ml-2000 pg/ml

Sensitivity

< 7.81 pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of human ENOX2. No significant cross-reactivity or interference between human ENOX2 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

70,082 Da

OMIM

300282

3D Structure

ModBase 3D Structure for Q16206

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ENOX2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENOX2 purchase

MBS943476 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ecto-NOX disulfide-thiol exchanger 2 (ENOX2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ENOX2. The ELISA analytical biochemical technique of the MBS943476 kit is based on ENOX2 antibody-ENOX2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ENOX2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ENOX2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ENOX2. It may not necessarily be applicable to this product.

NCBI GI #

528524612

NCBI GeneID

10495

NCBI Accession #

NP_001268665.1

UniProt Primary Accession #

Q16206

UniProt Secondary Accession #

Q5VTJ1; Q5VTJ2; Q8WUX0; Q9NTP6; Q9UH82; A8K197; A8K1C2

UniProt Related Accession #

Q16206

GenBank Nucleotide #

NM_001281736.1

NCBI Official Full Name

ecto-NOX disulfide-thiol exchanger 2 isoform a

NCBI Official Synonym Full Names

ecto-NOX disulfide-thiol exchanger 2

NCBI Official Symbol

ENOX2

NCBI Official Synonym Symbols

APK1; tNOX; COVA1

UniProt Protein Name

Ecto-NOX disulfide-thiol exchanger 2

UniProt Synonym Protein Names

APK1 antigen; Cytosolic ovarian carcinoma antigen 1; Tumor-associated hydroquinone oxidase; tNOX

Protein Family

Ecto-NOX disulfide-thiol exchanger

UniProt Gene Name

ENOX2

UniProt Synonym Gene Names

COVA1; tNOX

UniProt Entry Name

ENOX2_HUMAN

NCBI Protein Information

ecto-NOX disulfide-thiol exchanger 2; APK1 antigen; cytosolic ovarian carcinoma antigen 1; tumor-associated hydroquinone oxidase

NCBI Summary for ENOX2

This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

UniProt Comments for ENOX2

ENOX2: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. Belongs to the ENOX family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.-.-.-; Cytoskeletal; Cell surface

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: extracellular space; cytosol; external side of plasma membrane

Molecular Function: nucleic acid binding; nucleotide binding; protein disulfide oxidoreductase activity

Biological Process: regulation of growth; cell growth; ultradian rhythm

Research Articles on ENOX2

1. The results suggest that phosphorylation of serine-504 by PKCdelta modulates the biological function of tNOX.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ENOX2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6 publications with ENOX2 and Neoplasms
Stomach Neoplasms Antibodies	>2 publications with ENOX2 and Stomach Neoplasms
Adenocarcinoma Antibodies	>1 publications with ENOX2 and Adenocarcinoma
Melanoma Antibodies	>1 publications with ENOX2 and Melanoma
Colonic Neoplasms Antibodies	>1 publications with ENOX2 and Colonic Neoplasms
Colorectal Neoplasms Antibodies	>1 publications with ENOX2 and Colorectal Neoplasms
Pancreatic Neoplasms Antibodies	>1 publications with ENOX2 and Pancreatic Neoplasms
Ovarian Neoplasms Antibodies	>1 publications with ENOX2 and Ovarian Neoplasms
Prostatic Neoplasms Antibodies	>1 publications with ENOX2 and Prostatic Neoplasms
Breast Neoplasms Antibodies	>1 publications with ENOX2 and Breast Neoplasms

Organs/Tissues associated with ENOX2 elisa kit

Organ/Tissue Name	Pubmed Publications
Stomach Antibodies	>2 publications with ENOX2 and Stomach
Lung Antibodies	>2 publications with ENOX2 and Lung
Heart Antibodies	>1 publications with ENOX2 and Heart
Kidney Antibodies	>1 publications with ENOX2 and Kidney
Prostate Antibodies	>1 publications with ENOX2 and Prostate
Liver Antibodies	>1 publications with ENOX2 and Liver
Embryonic Tissue Antibodies	>1 publications with ENOX2 and Embryonic Tissue
Skin Antibodies	>1 publications with ENOX2 and Skin
Intestine Antibodies	>1 publications with ENOX2 and Intestine