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High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma (FCER1G) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS948435

MBS948435 is a recombinant protein targeting Fcer1g. Also known as Recombinant Mouse High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Fcer1g; Fce1g More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g), Recombinant Protein
Full Product Name
Recombinant Mouse High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g)
Product Gene Name
Fcer1g recombinant protein
Product Synonym Gene Name
Recombinant High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g); High affinity immunoglobulin epsilon receptor subunit gamma; Fc receptor gamma-chain; FcRgamma Fc-epsilon RI-gamma IgE Fc receptor subunit gamma; FceRI gamma
Sequence
LGEPQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
9,652 Da
Sequence Positions
19-23
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 1; NC_000067.6 (171229572..171234349, complement). Location: 1 H3; 1 79.23 cM
3D Structure
ModBase 3D Structure for P20491
Species
Mus musculus (Mouse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Fcer1g recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Fcer1g. It may not necessarily be applicable to this product.

NCBI GI #
6753830
NCBI GeneID
14127
NCBI Accession #
NP_034315.1
UniProt Primary Accession #
P20491
UniProt Related Accession #
P20491
GenBank Nucleotide #
NM_010185.4
NCBI Official Full Name
high affinity immunoglobulin epsilon receptor subunit gamma
NCBI Official Synonym Full Names
Fc receptor, IgE, high affinity I, gamma polypeptide
NCBI Official Symbol
Fcer1g
NCBI Official Synonym Symbols
CD23; Fce1g; Ly-50; FcR[g]; AI573376; FcRgamma; FcR-gamma; FcepsilonRI
UniProt Protein Name
High affinity immunoglobulin epsilon receptor subunit gamma
UniProt Synonym Protein Names
Fc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma
Protein Family
High affinity immunoglobulin epsilon receptor
UniProt Gene Name
Fcer1g
UniProt Synonym Gene Names
Fce1g; FcRgamma; FceRI gamma
UniProt Entry Name
FCERG_MOUSE
NCBI Protein Information
high affinity immunoglobulin epsilon receptor subunit gamma; fceRI gamma; fc-epsilon RI-gamma; Fc receptor gamma-chain; igE Fc receptor subunit gamma

UniProt Comments for Fcer1g

FCER1G: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. Belongs to the CD3Z/FCER1G family.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: cell surface; membrane; integral to plasma membrane; Fc-epsilon receptor I complex; integral to membrane; plasma membrane; external side of plasma membrane; lipid raft

Molecular Function: protein binding; transmembrane receptor activity; IgG binding; IgE binding; IgE receptor activity

Biological Process: positive regulation of immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; signal transduction; mast cell activation; positive regulation of interleukin-10 production; cell surface receptor linked signal transduction; negative regulation of mast cell apoptosis; positive regulation of phagocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class I; Fc receptor mediated stimulatory signaling pathway; integrin-mediated signaling pathway; neutrophil chemotaxis; regulation of immune response; positive regulation of type I hypersensitivity; positive regulation of interleukin-6 production; positive regulation of mast cell degranulation; positive regulation of type III hypersensitivity; positive regulation of tumor necrosis factor production; neutrophil activation during immune response; serotonin secretion by platelet; positive regulation of type IIa hypersensitivity; defense response to bacterium; immunoglobulin mediated immune response; positive regulation of mast cell cytokine production; phagocytosis, engulfment
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Research Articles on Fcer1g

1. Fcgamma receptor deficiency attenuates diabetic nephropathy in mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Fcer1g recombinant protein

 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 GPVI-mediated Activation Cascade Pathway antibodies  GPVI-mediated Activation Cascade Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Platelet Adhesion To Exposed Collagen Pathway antibodies  Platelet Adhesion To Exposed Collagen Pathway Diagram

Diseases associated with Fcer1g recombinant protein

 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >5 publications with Fcer1g and Hypersensitivity
 Genetic Predisposition to Disease Antibodies  >5 publications with Fcer1g and Genetic Predisposition to Disease
 Inflammation Antibodies  >3 publications with Fcer1g and Inflammation
 Asthma Antibodies  >2 publications with Fcer1g and Asthma
 Necrosis Antibodies  >2 publications with Fcer1g and Necrosis
 Neoplasms Antibodies  >2 publications with Fcer1g and Neoplasms
 Lung Diseases Antibodies  >2 publications with Fcer1g and Lung Diseases
 Fibrosis Antibodies  >1 publications with Fcer1g and Fibrosis
 Nervous System Malformations Antibodies  >1 publications with Fcer1g and Nervous System Malformations
 Weight Gain Antibodies  >1 publications with Fcer1g and Weight Gain

Organs/Tissues associated with Fcer1g recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with Fcer1g and Blood
 Brain Antibodies  >2 publications with Fcer1g and Brain
 Lung Antibodies  >1 publications with Fcer1g and Lung
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