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C-X-C Motif Chemokine 11 (SCYB11) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS949269

Chotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in… More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-X-C motif chemokine 11 (Scyb11), Recombinant Protein
Full Product Name
Recombinant Mouse C-X-C motif chemokine 11 protein
Product Gene Name
Scyb11 recombinant protein
Product Synonym Names
Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11
Sequence
FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQ
Host
E Coli
Form/Format
Liquid containing glycerol
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
12.9 kDa
Sequence Positions
22-98aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JHH5
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of Scyb11 recombinant protein

Mouse SCYB11 Recombinant Protein – Cat# MBS949269

Product References and Citations for Scyb11 recombinant protein

Cloning, genomic sequence, and chromosome mapping of scyb11, the murine homologue of SCYB11 (alias betaR1/H174/SCYB9B/I-TAC/IP-9/CXCL11) .Meyer M., Erdel M., Duba H.C., Werner E.R., Werner-Felmayer G.Cytogenet. Cell Genet. 88:278-282(2000) The murine chemokine CXCL11 (IFN-inducible T cell alpha chemoattractant) is an IFN-gamma- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia.Widney D.P., Xia Y.-R., Lusis A.J., Smith J.B.J. Immunol. 164:6322-6331(2000)

Other Notes

Small volumes of Scyb11 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Scyb11 purchase

MBS949269 is a recombinant protein targeting Scyb11. Also known as Recombinant Mouse C-X-C motif chemokine 11 protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Scyb11. It may not necessarily be applicable to this product.

NCBI GI #
9507071
NCBI GeneID
56066
NCBI Accession #
NP_062367.1
UniProt Primary Accession #
Q9JHH5
UniProt Related Accession #
Q9JHH5
GenBank Nucleotide #
NM_019494.1
NCBI Official Full Name
C-X-C motif chemokine 11
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 11
NCBI Official Symbol
Cxcl11
NCBI Official Synonym Symbols
Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11; Scyb9b; betaR1
UniProt Protein Name
C-X-C motif chemokine 11
UniProt Synonym Protein Names
Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11
Protein Family
C-X-C motif chemokine
UniProt Gene Name
Cxcl11
UniProt Synonym Gene Names
Scyb11; I-TAC
UniProt Entry Name
CXL11_MOUSE
NCBI Protein Information
C-X-C motif chemokine 11

UniProt Comments for Scyb11

CXCL11: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Chemokine
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Research Articles on Scyb11

1. These findings functionally integrate K17, hnRNP K, and gene expression along with RSK and CXCR3 signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Scyb11 recombinant protein

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram

Diseases associated with Scyb11 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >212 publications with Scyb11 and Inflammation
 Necrosis Antibodies  >92 publications with Scyb11 and Necrosis
 Lung Diseases Antibodies  >66 publications with Scyb11 and Lung Diseases
 Disease Models, Animal Antibodies  >60 publications with Scyb11 and Disease Models, Animal
 Liver Diseases Antibodies  >42 publications with Scyb11 and Liver Diseases
 Fibrosis Antibodies  >36 publications with Scyb11 and Fibrosis
 Cardiovascular Diseases Antibodies  >33 publications with Scyb11 and Cardiovascular Diseases
 Hypersensitivity Antibodies  >32 publications with Scyb11 and Hypersensitivity
 Kidney Diseases Antibodies  >26 publications with Scyb11 and Kidney Diseases
 Adenocarcinoma Antibodies  >21 publications with Scyb11 and Adenocarcinoma

Organs/Tissues associated with Scyb11 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >391 publications with Scyb11 and Blood
 Lung Antibodies  >93 publications with Scyb11 and Lung
 Liver Antibodies  >53 publications with Scyb11 and Liver
 Kidney Antibodies  >41 publications with Scyb11 and Kidney
 Brain Antibodies  >37 publications with Scyb11 and Brain
 Bone Marrow Antibodies  >27 publications with Scyb11 and Bone Marrow
 Eye Antibodies  >26 publications with Scyb11 and Eye
 Spleen Antibodies  >26 publications with Scyb11 and Spleen
 Thymus Antibodies  >11 publications with Scyb11 and Thymus
 Bladder Antibodies  >3 publications with Scyb11 and Bladder
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